Journal Articles
Orlowska, Marta K., Lor, Mary, Fitzsimmons, Rebecca L., Robinson, Harley, Delcheva, Iliana, Williams, Daniel, Priest, Craig and Hudson, James E. (2025). Robust and consistent bonding of polydimethylsiloxane to polystyrene cell culture plates. APL Materials, 13 (1) 011127. doi: 10.1063/5.0249862
Kok, Cindy Y., Tsurusaki, Shinya, Cabanes-Creus, Marti, Igoor, Sindhu, Rao, Renuka, Skelton, Rhys, Liao, Sophia H.Y., Ginn, Samantha L., Knight, Maddison, Scott, Suzanne, Mietzsch, Mario, Fitzsimmons, Rebecca, Miller, Jessica, Mohamed, Tamer M.A., McKenna, Robert, Chong, James J.H., Hill, Adam P., Hudson, James E., Alexander, Ian E., Lisowski, Leszek and Kizana, Eddy (2023). Development of new adeno-associated virus capsid variants for targeted gene delivery to human cardiomyocytes. Molecular Therapy - Methods and Clinical Development, 30, 459-473. doi: 10.1016/j.omtm.2023.08.010
Voges, Holly K., Foster, Simon R., Reynolds, Liam, Parker, Benjamin L., Devilée, Lynn, Quaife-Ryan, Gregory A., Fortuna, Patrick R.J., Mathieson, Ellen, Fitzsimmons, Rebecca, Lor, Mary, Batho, Christopher, Reid, Janice, Pocock, Mark, Friedman, Clayton E., Mizikovsky, Dalia, Francois, Mathias, Palpant, Nathan J., Needham, Elise J., Peralta, Marina, Monte-Nieto, Gonzalo del, Jones, Lynelle K., Smyth, Ian M., Mehdiabadi, Neda R., Bolk, Francesca, Janbandhu, Vaibhao, Yao, Ernestene, Harvey, Richard P., Chong, James J.H., Elliott, David A. ... Hudson, James E. (2023). Vascular cells improve functionality of human cardiac organoids. Cell Reports, 42 (5) 112322, 112322. doi: 10.1016/j.celrep.2023.112322
Wang, Peiqi, Hill, Timothy A., Mitchell, Justin, Fitzsimmons, Rebecca L., Xu, Weijun, Loh, Zhixuan, Suen, Jacky Y., Lim, Junxian, Iyer, Abishek and Fairlie, David P. (2022). Modifying a hydroxyl patch in glucagon-like peptide 1 produces biased agonists with unique signaling profiles. Journal of Medicinal Chemistry, 65 (17), 11759-11775. doi: 10.1021/acs.jmedchem.2c00653
Krycer, James R., Lor, Mary, Fitzsimmons, Rebecca L. and Hudson, James E. (2022). A cell culture platform for quantifying metabolic substrate oxidation in bicarbonate-buffered medium. Journal of Biological Chemistry, 298 (2) 101547, 1-9. doi: 10.1016/j.jbc.2021.101547
Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Gupta, Praveer K., Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J., Fairlie, David P. and Iyer, Abishek (2019). Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic Type 2 inflammation. British Journal of Pharmacology, 176 (19) bph.14768, 3775-3790. doi: 10.1111/bph.14768
Tuong, Zewen Kelvin, Fitzsimmons, Rebecca, Wang, Shu-Ching Mary, Oh, Tae Gyu, Lau, Patrick, Steyn, Frederik, Thomas, Gethin and Muscat, George E. O. (2016). Transgenic adipose-specific expression of the nuclear receptor RORα drives a striking shift in fat distribution and impairs glycemic control. EBioMedicine, 11, 101-117. doi: 10.1016/j.ebiom.2016.08.027
Lau, Patrick, Tuong, Zewen K., Wang, Shu-Ching, Fitzsimmons, Rebecca L., Goode, Joel M., Thomas, Gethin P., Cowin, Gary J., Pearen, Michael A., Mardon, Karine, Stow, Jennifer L. and Muscat, George E. O. (2015). Ror-alpha deficiency and decreased adiposity are associated with induction of thermogenic gene expression in subcutaneous white and brown adipose tissue. American Journal of Physiology: Endocrinology and Metabolism, 308 (2), E159-E171. doi: 10.1152/ajpendo.00056.2014
Pearen, Michael A., Goode, Joel M., Fitzsimmons, Rebecca L., Eriksson, Natalie A., Thomas, Gethin P., Cowin, Gary J., Wang, S.-C. Mary, Tuong, Zewen K. and Muscat, George E. O. (2013). Muscle specific Nor-1 expression regulates multiple pathways that effect adiposity, metabolism and endurance. Molecular Endocrinology, 27 (11), 1897-1917. doi: 10.1210/me.2013-1205
Fernández Rojo, Manuel, Gongora, Milena, Fitzsimmons, Rebecca L., Martel, Nick, Martin, Sheree D., Nixon, Susan, Brooks, Andrew J., Ikonomopoulou, Maria P., Martin, Sally, Lo, Harriet P., Myers, Stephen A., Restall, Christina, Ferguson, Charles, Pilch, Paul F., McGee, Sean L., Anderson, Robin L., Waters, Michael J., Hancock, John F., Grimmond, Sean M., Muscat, George E. and Parton, Robert G. (2013). Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling. Cell Reports, 4 (2), 238-247. doi: 10.1016/j.celrep.2013.06.017
Diaz, Marianne, Martel, Nick, Fitzsimmons, Rebecca L., Eriksson, Natalie A., Cowin, Gary J., Thomas, Gethin P., Lê Cao, Kim-Anh, Muscat, George E. O. and Leong, Gary M. (2012). Ski overexpression in skeletal muscle modulates genetic programs that control susceptibility to diet-induced obesity and insulin signaling. Obesity, 20 (11), 2157-2167. doi: 10.1038/oby.2012.101
Fitzsimmons, Rebecca L., Lau, Patrick and Muscat, George E. (2012). Retinoid-related orphan receptor alpha and the regulation of lipid homeostasis. The Journal of Steroid Biochemistry and Molecular Biology, 130 (3-5), 159-168. doi: 10.1016/j.jsbmb.2011.06.009
Pearen, Michael A., Eriksson, Natalie A., Fitzsimmons, Rebecca L., Goode, Joel M., Martel, Nick, Andrikopoulos, Sofianos and Muscat, George E. O. (2012). The nuclear receptor, Nor-1, markedly increases type II oxidative muscle fibers and resistance to fatigue. Molecular Endocrinology, 26 (3), 372-384. doi: 10.1210/me.2011-1274
Lau, P., Fitzsimmons, R. L., Pearen, M. A., Watt, M. J. and Muscat, G. E. O. (2011). Homozygous staggerer (sg/sg) mice display improved insulin sensitivity and enhanced glucose uptake in skeletal muscle. Diabetologia, 54 (5), 1169-1180. doi: 10.1007/s00125-011-2046-3
Wang, Scm, Myers, SA, Eriksson, NA, Fitzsimmons, RL and Muscat, GEO (2011). Nr4a1 siRNA expression attenuates alpha-MSH regulated gene expression in 3T3-L1 adipocytes. Molecular Endocrinology, 25 (2), 291-306. doi: 10.1210/me.2010-0231
Raichur, S., Fitzsimmons, R. L., Myers, S. A., Pearen, M. A., Lau, P., Eriksson, N., Wang, S. M. and Muscat, G. E. O. (2010). Identification and validation of the pathways and functions regulated by the orphan nuclear receptor, ROR alpha1, in skeletal muscle. Nucleic Acids Research., 38 (13) gkq180, 4296-4312. doi: 10.1093/nar/gkq180
Lau, Patrick, Fitzsimmons, Rebecca L., Raichur, Suryaprakash, Wang, Shu-Ching M., Lechtken, Adriane and Muscat, George E. O. (2008). The orphan nuclear receptor, ROR alpha, regulates gene expression that controls lipid metabolism - Staggerer (sg/sg) mice are resistant to diet-induced obesity. The Journal of Biological Chemistry, 283 (26), 18411-18421. doi: 10.1074/jbc.M710526200
Zhang, Xingqi, Fitzsimmons, Rebecca L., Cleland, Leslie G., Ey, Peter L, Zannettino, Andrew C. W., Farmer, Elizabeth-Anne, Sincock, Paul and Mayrhofer, Graham (2003). CD36/fatty acid translocase in rats: Distribution, isolation from hepatocytes, and comparison with the scavenger receptor SR-B1. Laboratory Investigation, 83 (3), 317-332. doi: 10.1097/01.LAB.0000059923.67198.BA
Conference Papers
Iyer, Abishek, Loh, Zhixuan, Fitzsimmons, Rebecca L., Reid, Robert C., Ramnath, Divya, Clouston, Andrew, Irvine, Katharine M., Powell, Elizabeth E., Schroder, Kate, Stow, Jennifer L., Sweet, Matthew J. and Fairlie, David P. (2019). Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation. Experimental Biology Meeting (EB), Orlando Fl, Apr 06-09, 2019. HOBOKEN: WILEY.
Diaz, M, Martel, N, Fitzsimmons, R, Pearen, M, Muscat, GE and Leong, GM (2010). c-Ski Transgenic Mice Are Resistant to Diet-Induced Obesity.. 92nd Meeting and Expo of the Endocrine Society (ENDO 2010), San Diego CA, JUN 19-22, 2010.