Speaker

Dr Amirali Popat

Title

Emerging trends in stimuli responsive nanomaterials for oral drug delivery

Abstract

The development of reliable oral delivery systems for problem drugs and biologics is one of the biggest challenges faced by the pharmaceutical industry in recent times. Despite this oral route of administration remains the most preferred route for the application of pharmaceuticals, due to its ease of administration and patience compliance. However, oral delivery of many small molecule drugs and most of the peptide drugs is challenging due to hostile environment in gastrointestinal tract, poor solubility and permeability. This results in their limited commercial use, as well as serious clinical development trade-offs that often result in poor efficacy and side effects associated with it. Therefore there is a compelling need for development of new generation of stimuli responsive materials with high loading capacity, and improved site specific delivery. We have developed several generation of mesoporous silica nanoparticles based materials for oral delivery of small molecules and macromolecules. Given that it takes more than 2 decades for a drug to become clinically available, our platform technology could provide much-needed impetus in the area of oral drug delivery of challenging molecules

Speaker Bio

Dr Amirali Popatis a Senior Research Fellow at the School of Pharmacy, The University of Queensland. His group’s research interests include the design of programmable nano formulations for personalised treatment of Inflammatory Bowel Disease, Cancer and Diabetes. Dr. Popat has an excellent track record and international standing in the area of novel drug delivery systems evidenced by > 30 peer reviewed publications and 2 patents. Most of these publications are in top tier journals in the fields of Chemistry (Angweandte Chemie, Chem Comm), Biomaterials (Biomaterials, Nanoscale), and Pharmaceutical Science (Mol Pharm, Int J Pharm, J Colloids & Interface Sci). Together these have a combined ISI I.F of >150 with ~1500 citations with an H-Index of 20. Testimony to his excellence in research, teaching and community engagement he has received many awards notably 2018 QLD Young Tall Poppy Science Award and Faculty Early Career Research Excellence Award.

About Seminar Series

The School of Pharmacy Seminar Series involves regular formal presentations of high-quality scholarly work with broad appeal.

The wider School community is invited to attend, including academic and professional staff, special guests, visitors, as well as HDR, postgraduate, masters and honours students.

Seminars are held on Fridays from 12pm–1pm in room 5034 in the Pharmacy Australia Centre of Excellence, 20 Cornwall St Woolloongabba (next to TRI and the PA Hospital).

Confirmed 2021 seminars

Date Presenter
12-1pm, Friday 19 March
(PACE R5034 and Zoom)
Professor Paul Clarke, Director Diamantina Institute        
12-1pm, Friday 16 April
(Zoom only)
Associate Professor Francine Marques, Monash University     
12-1pm, Friday 23 April
(Zoom only)
Associate Professor Ben Colagiuri, Sydney University 
12-1pm, Friday 7 May
(Zoom only)
Dr Laurence Cheung, Curtin University
12-1pm, Friday 30 July
(location TBC)
Dr Gary Chan, UQ CYSUR
12-1pm, Friday 13 August
(Zoom only)
Professor Sanjay Garg, University of South Australia
12-1pm, Friday 3 September
(PACE R5034 and Zoom)
Associate Professor Michael Barras, UQ Pharmacy
12-1pm 10 September
(Online via Zoom)

Professor Josephine Forbes, Mater Research

 

12-1pm, Friday 17 September
(PACE R5034 and Zoom)

Professor Nigel McMillan, Program Director: Infectious Diseases and Immunology, Menzies Health Institute QLD, Griffith University

12-1pm, Friday 24 September
(Location TBC)
Denuja Karunakaran, IMB Fellow, Institute for Molecular Bioscience (IMB), UQ

Venue

Pharmacy Australia Centre of Excellence, 20 Cornwall St, Woolloongabba
Room: 
5034