Dr Karnaker Reddy Tupally
Senior Research Assistant
School of Pharmacy
Honorary Research Fellow
School of Pharmacy and Pharmaceutical Sciences

Publications
Book
Singh, Prachi, Kokil, Ganesh R., Tupally, Karnaker R., Poddar, Kingshuk, Tan, Aaron, Venkatesan, Venky, Parekh, Harendra S. and Pastorin, Giorgia (2016). Therapeutic perspectives in Type-1 Diabetes. Singapore: Springer. doi: 10.1007/978-981-10-0602-9
Book Chapters
Tupally, Karnaker Reddy, Seal, Prasenjit, Pandey, Preeti, Lohman, Rink-Jan, Smith, Sean, Ouyang, Defang and Parekh, Haredra (2024). Integration of dendrimer-based delivery technologies with computational pharmaceutics and their potential in the era of nanomedicine. Exploring computational pharmaceutics - AI and modeling in Pharma 4.0. (pp. 328-378) edited by Defang Ouyang. Hoboken, NJ, United States: Wiley. doi: 10.1002/9781119987260.ch10
Singh, Prachi, Kokil, Ganesh R., Tupally, Karnaker R., Poddar, Kingshuk, Tan, Aaron, Venkatesan, Venky, Parekh, Harendra S. and Pastorin, Giorgia (2016). Introduction to diabetes and type 1 diabetes. Therapeutic perspectives in type-1 diabetes. (pp. 1-6) edited by Prachi Singh, Ganesh R. Kokil, Karnaker R. Tupally, Kingshuk Poddar, Aaron Tan, Venky Venkatesan, Harendra S. Parekh and Giorgia Pastorin. Singapore, Singapore: Springer. doi: 10.1007/978-981-10-0602-9_1
Tupally, Karnaker R., Kokil, Ganesh K., Thakur, Sachin S., Singh, Prachi and Parekh, Harendra S. (2015). Dendrimers. Controlled release systems: advances in nanobottles and active nanoparticles. (pp. 259-286) edited by Alexander van Herk, Jacqueline Forcada and Giorgia Pastorin. Boca Raton, FL, United States: Taylor & Francis. doi: 10.1201/b19860-15
Seefeld, Anne, Kokil, Ganesh R., Tupally, Karnaker R., Parekh, Harendra S. and Herten, Dirk-Peter (2013). Fluorescent nucleic acid probes in living cells. DNA and RNA nanobiotechnologies in medicine: diagnosis and treatment of diseases. (pp. 291-328) edited by Volker A. Erdmann and Jan Barciszewski. Berlin, Germany: Springer. doi: 10.1007/978-3-642-36853-0_12
Journal Articles
Almahmoud, Abdallah, Parekh, Harendra S., Paterson, Brett M., Tupally, Karnaker Reddy, Cowin, Gary J., Nguyen, Ai, Gulzar, Arif and Vegh, Viktor (2026). Development and characterisation of a thermoreversible sol–gel for intranasal delivery of MRI and PET imaging agents. International Journal of Pharmaceutics, 690 126517, 1-15. doi: 10.1016/j.ijpharm.2025.126517
Almahmoud, Abdallah, Parekh, Harendra S., Paterson, Brett M., Tupally, Karnaker Reddy and Vegh, Viktor (2024). Intranasal delivery of imaging agents to the brain. Theranostics, 14 (13), 5022-5101. doi: 10.7150/thno.98473
Harrop, Angus C. F., Tupally, Karnaker R., Pandey, Preeti and Parekh, Harendra S. (2023). Opportunities for bioactive glass in gastrointestinal conditions: a review of production methodologies, morphology, composition, and performance. Molecular Pharmaceutics, 20 (12), 5954-5980. doi: 10.1021/acs.molpharmaceut.3c00188
Lohman, Rink-Jan, Tupally, Karnaker Reddy, Kandale, Ajit, Cabot, Peter J and Parekh, Harendra S (2023). Design and development of novel, short, stable dynorphin-based opioid agonists for safer analgesic therapy. Frontiers in Pharmacology, 14 1150313, 1150313-14. doi: 10.3389/fphar.2023.1150313
Rad, Isaac J., Chapman, Luke, Tupally, Karnaker Reddy, Veidt, Martin, Al-Sadiq, Hussain, Sullivan, Robert and Parekh, Harendra S (2023). A systematic review of ultrasound-mediated drug delivery to the eye and critical insights to facilitate a timely path to the clinic. Theranostics, 13 (11), 3582-3638. doi: 10.7150/thno.82884
AlSadiq, Hussain, Tupally, Karnaker Reddy, Vogel, Robert, Parekh, Harendra S. and Veidt, Martin (2022). Multi-physics study of acoustofluidic delivery agents' clustering behavior. Physics in Medicine and Biology, 67 (1) 015002, 015002. doi: 10.1088/1361-6560/ac4666
Alsadiq, Hussain, Tupally, Karnaker, Vogel, Robert, Kokil, Ganesh, Parekh, Harendra S. and Veidt, Martin (2021). Shell properties and concentration stability of acoustofluidic delivery agents. Physical and Engineering Sciences in Medicine, 44 (1), 79-91. doi: 10.1007/s13246-020-00954-4
Alsenani, Faisal, Tupally, Karnaker R., Chua, Elvis T., Eltanahy, Eladl, Alsufyani, Hamed, Parekh, Harendra S. and Schenk, Peer M. (2020). Evaluation of microalgae and cyanobacteria as potential sources of antimicrobial compounds. Saudi Pharmaceutical Journal, 28 (12), 1834-1841. doi: 10.1016/j.jsps.2020.11.010
de Luca, Sergio, Seal, Prasenjit, Parekh, Harendra S., Tupally, Karnaker R. and Smith, Sean C. (2020). Cell membrane penetration without pore formation: chameleonic properties of dendrimers in response to hydrophobic and hydrophilic environments. Advanced Theory and Simulations, 3 (7) 1900152, 1900152. doi: 10.1002/adts.201900152
Jing, Jing, Tupally, Karnaker R., Kokil, Ganesh R., Qu, Zhi, Chen, Sibao and Parekh, Harendra S. (2019). Development of a hybrid peptide dendrimer micellar carrier system and its application in the reformulation of a hydrophobic therapeutic agent derived from traditional Chinese medicine. RSC Advances, 9 (5), 2458-2463. doi: 10.1039/c8ra09606f
Shetty, Pallavi Krishna, Manikkath, Jyothsna, Tupally, Karnaker, Kokil, Ganesh, Hegde, Aswathi R., Raut, Sushil Y., Parekh, Harendra S. and Mutalik, Srinivas (2017). Skin delivery of EGCG and silibinin: potential of peptide dendrimers for enhanced skin permeation and deposition. AAPS PharmSciTech, 18 (6), 2346-2357. doi: 10.1208/s12249-017-0718-0
Hegde, Aswathi R., Rewatkar, Prarthana V., Manikkath, Jyothsna, Tupally, Karnaker, Parekh, Harendra S. and Mutalik, Srinivas (2017). Peptide dendrimer-conjugates of ketoprofen: synthesis and ex vivo and in vivo evaluations of passive diffusion, sonophoresis and iontophoresis for skin delivery. European Journal of Pharmaceutical Sciences, 102, 237-249. doi: 10.1016/j.ejps.2017.03.009
Conference Papers
Saifuddin, D., Lohman, R.-J., Tupally, K., Parekh, H. and Cabot, P. (2023). Bivalent kappa-selective opioid peptides with enhanced metabolic stability and potency. 81st FIP World Congress Of Pharmacy And Pharmaceutical Sciences, Brisbane, QLD Australia, 24-28 September 2023. PKP Publishing.
AL-Sadiq, H. A., Tupally, K. R., Parekh, H S. and M Veidt, M. (2021). Shell properties of a new acoustofluidic delivery agent. EPSM 2020, Engineering and Physical Sciences in Medicine, Brisbane, QLD Australia, 28-29 October 2020. Dordrecht, Netherlands: Springer Netherlands.
Saifuddin, Danial, Lohman, Rink-Jan, Tupally, Karnaker Reddy, Parekh, Harendra S. and Cabot, Peter J. (2021). Novel opioid peptides as allosteric modulators of nociception. ASMR medical research week: Queensland virtual symposium, Online, 9-10 June 2021.
Alsadiq, H., Tupally, K. R., Kokil, G. R., Vogel, R., Parekh, H. S. and Veidt, M. (2019). Concentration stability of monolayer and bilayer lipid microbubbles–a precursor for new drug delivery applications. Drug Delivery Australia 2019 Conference, Brisbane, QLD Australia, 18-19 November 2019.
Alsadiq, Hussain, Reddy, Karnaker, Parekh, Harendra and Veidt, Martin (2018). Influence of acoustofluidic parameters on velocity streaming of sonicated medical microbubbles. AAS2018: Acoustics 2018: Hear to Listen, Adelaide, SA Australia, 6-9 November 2018. Adelaide, SA Australia: Australian Acoustical Society.
Thesis
Tupally, Karnaker Reddy (2016). Engineering novel, steric stabilized disulfide-containing amino acids and their application in carrier system, therapeutic peptide and FRET-probe synthesis. PhD Thesis, School of Pharmacy, The University of Queensland. doi: 10.14264/390469
Patents
Tupally, Karnaker, Cabot, Peter, Nandkumar, Ajit and Parekh, Harendra (2024). Peptides and uses thereof. EP4175970A1.
Parekh, Harendra and Tupally, Karnaker Reddy (2023). Disulfide bond containing compounds and uses thereof. US11566044B2.
Parekh, Harendra, Tupally, Karnaker, Cabot, Peter and Kandale, Ajit (2021). Peptides and uses thereof. 2021300202.
Parekh, Harendra, Cabot, Peter, Tupally, Karnaker and Kandale, Ajit (2020). A Cyclic Peptide. US-20220089646-A1.
Parekh, Harendra, Cabot, Peter, Tupally, Karnaker and Kandale, Ajit (2020). A cyclic peptide. 2020212659.