Dr Ajit Kandale

Lohman, Rink-Jan, Tupally, Karnaker Reddy, Kandale, Ajit, Cabot, Peter J and Parekh, Harendra S (2023). Design and development of novel, short, stable dynorphin-based opioid agonists for safer analgesic therapy. Frontiers in Pharmacology, 14 1150313, 1150313-14. doi: 10.3389/fphar.2023.1150313

Lohman, Rink-Jan, Tupally, Karnaker Reddy, Kandale, Ajit, Cabot, Peter J. and Parekh, Harendra S. (2022). Design and development of novel, short, stable dynorphin-based opioid agonists for safer analgesic therapy. British Journal of Pharmacology, 180 (1), 129-129. doi: 10.1111/bph.15862

Lv, You, Zheng, Shan, Goldenzweig, Adi, Liu, Fengjiang, Gao, Yan, Yang, Xiuna, Kandale, Ajit, McGeary, Ross P., Williams, Simon, Kobe, Bostjan, Schembri, Mark A., Landsberg, Michael J., Wu, Bin, Brück, Thomas B., Sieber, Volker, Boden, Mikael, Rao, Zihe, Fleishman, Sarel J., Schenk, Gerhard and Guddat, Luke W. (2022). Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform Chemicals. Applied Biosciences, 1 (2), 163-178. doi: 10.3390/applbiosci1020011

Patel, Khushboo, Teran, David, Zheng, Shan, Kandale, Ajit, Garcia, Mario, Lv, You, Schembri, Mark A, McGeary, Ross P, Schenk, Gerhard and Guddat, Luke William (2017). Crystal structures of Staphylococcus aureus ketol-acid reductoisomerase in complex with two transition state analogs that have biocidal activity. Chemistry- A European Journal, 23 (72), 18289-18295. doi: 10.1002/chem.201704481

You, Lv, Kandale, Ajit, Wun, Shun Jie, McGeary, Ross P., Williams, Simon J., Kobe, Bostjan, Sieber, Volker, Schembri, Mark A., Schenk, Gerhard and Guddat, Luke W. (2016). Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution: A potential target for anti-tuberculosis drug discovery. Febs Journal, 283 (7), 1184-1196. doi: 10.1111/febs.13672

Talluri, Sirishadevi, Kini, Suvarna G., Kandale, Ajit, Kumar, Ganesh and Ohlyan, Renu (2014). Synthesis and in vitro cholesteryl ester transfer protein inhibitory activity of novel esters of 2, 10-dichloro-12H-dibenzo [d,g] 1,3-dioxocin-6-carboxylic acid. Medicinal Chemistry Research, 23 (10), 4491-4499. doi: 10.1007/s00044-014-1021-1

Ohlyan, Renu, Kandale, Ajit and Yadav, Amarjeet (2014). Pharmacognostic evaluation and antibacterial activity of dry fruits of Piper attenuatum buch-ham. International Journal of Pharmacy and Pharmaceutical Sciences, 6 (2), 402-406.

Kandale, Ajit, Ohlyan, Renu and Kumar, Ganesh (2014). Synthesis and in-vitro antiproliferative activity of 2, 3-aryl substituted 1, 3-benzoxazin-4-one derivatives. International Journal of Pharmacy and Pharmaceutical Sciences, 6 (7), 68-71.

Deora, Girdhar Singh, Joshi, Prashant, Rathore, Vandana, Kumar, K. Lalith, Ohlyan, Renu and Kandale, Ajit (2013). Pharmacophore modeling and 3D QSAR analysis of isothiazolidinedione derivatives as PTP1B inhibitors. Medicinal Chemistry Research, 22 (7), 3478-3484. doi: 10.1007/s00044-012-0349-7

Rambabu, D., Murthy, P. V. N. S., Prasad, K. R. S., Kandale, Ajit, Deora, Girdhar Singh, Rao, M. V. Basaveswara and Pal, Manojit (2013). ChemInform Abstract: AgNO3Mediated C-N Bond Forming Reaction: Synthesis of 3-Substituted Benzothiazines as Potential COX Inhibitors. ChemInform, 44 (12), no-no. doi: 10.1002/chin.201312167

Ohlyan, Renu, Kandale, Ajit, Deora, Girdhar Singh, Rathore, Vandana and Chahal, Jagbir (2013). In vitro screening of dry fruit extracts of Piper attenuatum for antioxidant and anticancer activity. Medicinal Chemistry Research, 22 (3), 1365-1370. doi: 10.1007/s00044-012-0122-y

Rambabu, D., Kumar, S. Kiran, Sreenivas, B. Yogi, Sandra, Sandhya, Kandale, Ajit, Misra, Parimal, Rao, M. V. Basaveswara and Pal, Manojit (2013). Ultrasound-based approach to spiro-2,3-dihydroquinazolin-4(1H)-ones: their in vitro evaluation against chorismate mutase. Tetrahedron Letters, 54 (6), 495-501. doi: 10.1016/j.tetlet.2012.11.057

Prasad, Bagineni, Shiva Kumar, K., Vijaya Babu, P., Anusha, K., Rambabu, D., Kandale, Ajit, Vanaja, G.R., Kalle, Arunasree M. and Pal, Manojit (2012). AlCl3 induced C–N bond formation followed by Pd/C–Cu mediated coupling–cyclization strategy: synthesis of pyrrolo[2,3-b]quinoxalines as anticancer agents. Tetrahedron Letters, 53 (45), 6059-6066. doi: 10.1016/j.tetlet.2012.08.119

Rambabu, D., Murthy, P. V. N. S., Prasad, K. R. S., Kandale, Ajit, Deora, Girdhar Singh, Rao, M. V. Basaveswara and Pal, Manojit (2012). AgNO3 mediated C-N bond forming reaction: synthesis of 3-substituted benzothiazines as potential COX inhibitors. Tetrahedron Letters, 53 (48), 6577-6583. doi: 10.1016/j.tetlet.2012.09.102

Adepu, Raju, Kumar, K. Shiva, Sandra, Sandhya, Rambabu, D., Krishna, G. Rama, Reddy, C. Malla, Kandale, Ajit, Misra, Parimal and Pal, Manojit (2012). C-N bond formation under Cu-catalysis: synthesis and in vitro evaluation of N-aryl substituted thieno[2,3-d]pyrimidin-4(3H)-ones against chorismate mutase. Bioorganic & Medicinal Chemistry, 20 (17), 5127-5138. doi: 10.1016/j.bmc.2012.07.011

Kumar, T. Bhaskar, Sumanth, Ch., Vaishaly, S., Rao, M. Srinivasa, Sekhar, K. B. Chandra, Meda, Chandana Lakshmi T., Kandale, Ajit, Rambabu, D., Krishna, G. Rama, Reddy, C. Malla, Kumar, K. Shiva, Parsa, Kishore V. L. and Pal, Manojit (2012). Pd-mediated functionalization of polysubstituted pyrroles: their evaluation as potential inhibitors of PDE4. Bioorganic & Medicinal Chemistry Letters, 22 (17), 5639-5647. doi: 10.1016/j.bmcl.2012.06.100

Adepu, Raju, Rambabu, D., Prasad, Bagineni, Meda, Chandana Lakshmi T., Kandale, Ajit, Rama Krishna, G., Malla Reddy, C., Chennuru, Lakshmi N., Parsa, Kishore V. L. and Pal, Manojit (2012). Novel thieno[2,3-d]pyrimidines: Their design, synthesis, crystal structure analysis and pharmacological evaluation. Organic and Biomolecular Chemistry, 10 (29), 5554-5569. doi: 10.1039/c2ob25420d

Gorja, Dhilli Rao, Kumar, K. Shiva, Kandale, Ajit, Meda, Chandana Lakshmi T., Parsa, Kishore V. L., Mukkanti, K. and Pal, Manojit (2012). ChemInform Abstract: Design and Synthesis of 4-Alkynyl Pyrazoles as Inhibitors of PDE4: A Practical Access via Pd/C-Cu Catalysis. ChemInform, 43 (34), no-no. doi: 10.1002/chin.201234113

Reddy, T. Shyamsunder, Kumar, K. Shiva, Meda, Chandana L. T., Kandale, Ajit, Rambabu, D., Krishna, G. Rama, Hariprasad, C., Rao, V. Venugopala, Venkataiah, S., Reddy, C. Malla, Naidu, A., Dubey, P. K., Parsa, Kishore V. L. and Pal, Manojit (2012). Conformationally restricted novel pyrazole derivatives: synthesis of 1,8-disubstituted 5,5-dimethyl-4,5-dihydro-1H-benzo[g]indazoles as a new class of PDE4 inhibitors. Bioorganic & Medicinal Chemistry Letters, 22 (9), 3248-3255. doi: 10.1016/j.bmcl.2012.03.029

Gorja, Dhilli Rao, Kumar, K. Shiva, Kandale, Ajit, Meda, Chandana Lakshmi T., Parsa, Kishore V. L., Mukkanti, K. and Pal, Manojit (2012). Design and synthesis of 4-alkynyl pyrazoles as inhibitors of PDE4: a practical access via Pd/C-Cu catalysis. Bioorganic & Medicinal Chemistry Letters, 22 (7), 2480-2487. doi: 10.1016/j.bmcl.2012.02.008

Reddy, G. Rajeshwar, Reddy, T. Ram, Joseph, Suju C., Reddy, K. Sateesh, Meda, Chandana Lakshmi T., Kandale, Ajit, Rambabu, D., Krishna, G. Rama, Reddy, C. Malla, Parsa, Kishore V. L., Kumar, K. Shiva and Pal, Manojit (2012). Yb(OTf)(3) mediated MCR: a new and regioselective approach towards polysubstituted pyrroles of pharmacological interest. RSC Advances, 2 (24), 9142-9150. doi: 10.1039/c2ra21343e

Chahal, Jagbeer, Ohlyan, Renu, Kandale, Ajit, Walia, Anu and Puri, Sidharth (2011). Introduction, phytochemistry, traditional uses and biological activity of genus Piper: a review. International Journal of Current Pharmaceutical Review and Research, 2 (2), 130-144.

Parekh, Harendra, Tupally, Karnaker, Cabot, Peter and Kandale, Ajit (2021). Peptides and uses thereof. 2021300202.

Parekh, Harendra, Cabot, Peter, Tupally, Karnaker and Kandale, Ajit (2020). A Cyclic Peptide. US-20220089646-A1.

Parekh, Harendra, Cabot, Peter, Tupally, Karnaker and Kandale, Ajit (2020). A cyclic peptide. 2020212659.

Dr Ajit Kandale

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