Dr Ajit Kandale
Postdoctoral Research Fellow
School of Pharmacy
Publications
Journal Articles
Patel, Khushboo M., Teran, David, Zheng, Shan, Kandale, Ajit, Garcia, Mario, Lv, You, Schembri, Mark A., McGeary, Ross P., Schenk, Gerhard and Guddat, Luke W. (2017) Crystal structures of Staphylococcus aureus ketol-acid reductoisomerase in complex with two transition state analogues that have biocidal activity. Chemistry- A European Journal, 23 72: 18289-18295. doi:10.1002/chem.201704481
You, Lv, Kandale, Ajit, Wun, Shun Jie, McGeary, Ross P., Williams, Simon J., Kobe, Bostjan, Sieber, Volker, Schembri, Mark A., Schenk, Gerhard and Guddat, Luke W. (2016) Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution: A potential target for anti-tuberculosis drug discovery. Febs Journal, 283 7: 1184-1196. doi:10.1111/febs.13672
Talluri, Sirishadevi, Kini, Suvarna G., Kandale, Ajit, Kumar, Ganesh and Ohlyan, Renu (2014) Synthesis and in vitro cholesteryl ester transfer protein inhibitory activity of novel esters of 2, 10-dichloro-12H-dibenzo [d,g] 1,3-dioxocin-6-carboxylic acid. Medicinal Chemistry Research, 23 10: 4491-4499. doi:10.1007/s00044-014-1021-1
Kandale, Ajit, Ohlyan, Renu and Kumar, Ganesh (2014) Synthesis and in-vitro antiproliferative activity of 2, 3-aryl substituted 1, 3-benzoxazin-4-one derivatives. International Journal of Pharmacy and Pharmaceutical Sciences, 6 7: 68-71.
Ohlyan, Renu, Kandale, Ajit and Yadav, Amarjeet (2014) Pharmacognostic evaluation and antibacterial activity of dry fruits of Piper attenuatum buch-ham. International Journal of Pharmacy and Pharmaceutical Sciences, 6 2: 402-406.
Deora, Girdhar Singh, Joshi, Prashant, Rathore, Vandana, Kumar, K. Lalith, Ohlyan, Renu and Kandale, Ajit (2013) Pharmacophore modeling and 3D QSAR analysis of isothiazolidinedione derivatives as PTP1B inhibitors. Medicinal Chemistry Research, 22 7: 3478-3484. doi:10.1007/s00044-012-0349-7
Rambabu, D., Murthy, P. V. N. S., Prasad, K. R. S., Kandale, Ajit, Deora, Girdhar Singh, Rao, M. V. Basaveswara and Pal, Manojit (2013) ChemInform Abstract: AgNO3Mediated C-N Bond Forming Reaction: Synthesis of 3-Substituted Benzothiazines as Potential COX Inhibitors. ChemInform, 44 12: . doi:10.1002/chin.201312167
Ohlyan, Renu, Kandale, Ajit, Deora, Girdhar Singh, Rathore, Vandana and Chahal, Jagbir (2013) In vitro screening of dry fruit extracts of Piper attenuatum for antioxidant and anticancer activity. Medicinal Chemistry Research, 22 3: 1365-1370. doi:10.1007/s00044-012-0122-y
Rambabu, D., Kumar, S. Kiran, Sreenivas, B. Yogi, Sandra, Sandhya, Kandale, Ajit, Misra, Parimal, Rao, M. V. Basaveswara and Pal, Manojit (2013) Ultrasound-based approach to spiro-2,3-dihydroquinazolin-4(1H)-ones: their in vitro evaluation against chorismate mutase. Tetrahedron Letters, 54 6: 495-501. doi:10.1016/j.tetlet.2012.11.057
Prasad, Bagineni, Shiva Kumar, K., Vijaya Babu, P., Anusha, K., Rambabu, D., Kandale, Ajit, Vanaja, G.R., Kalle, Arunasree M. and Pal, Manojit (2012) AlCl3 induced C–N bond formation followed by Pd/C–Cu mediated coupling–cyclization strategy: synthesis of pyrrolo[2,3-b]quinoxalines as anticancer agents. Tetrahedron Letters, 53 45: 6059-6066. doi:10.1016/j.tetlet.2012.08.119
Rambabu, D., Murthy, P. V. N. S., Prasad, K. R. S., Kandale, Ajit, Deora, Girdhar Singh, Rao, M. V. Basaveswara and Pal, Manojit (2012) AgNO3 mediated C-N bond forming reaction: synthesis of 3-substituted benzothiazines as potential COX inhibitors. Tetrahedron Letters, 53 48: 6577-6583. doi:10.1016/j.tetlet.2012.09.102
Kumar, T. Bhaskar, Sumanth, Ch., Vaishaly, S., Rao, M. Srinivasa, Sekhar, K. B. Chandra, Meda, Chandana Lakshmi T., Kandale, Ajit, Rambabu, D., Krishna, G. Rama, Reddy, C. Malla, Kumar, K. Shiva, Parsa, Kishore V. L. and Pal, Manojit (2012) Pd-mediated functionalization of polysubstituted pyrroles: their evaluation as potential inhibitors of PDE4. Bioorganic & Medicinal Chemistry Letters, 22 17: 5639-5647. doi:10.1016/j.bmcl.2012.06.100
Adepu, Raju, Kumar, K. Shiva, Sandra, Sandhya, Rambabu, D., Krishna, G. Rama, Reddy, C. Malla, Kandale, Ajit, Misra, Parimal and Pal, Manojit (2012) C-N bond formation under Cu-catalysis: synthesis and in vitro evaluation of N-aryl substituted thieno[2,3-d]pyrimidin-4(3H)-ones against chorismate mutase. Bioorganic & Medicinal Chemistry, 20 17: 5127-5138. doi:10.1016/j.bmc.2012.07.011
Adepu, Raju, Rambabu, D., Prasad, Bagineni, Meda, Chandana Lakshmi T., Kandale, Ajit, Rama Krishna, G., Malla Reddy, C., Chennuru, Lakshmi N., Parsa, Kishore V. L. and Pal, Manojit (2012) Novel thieno[2,3-d]pyrimidines: Their design, synthesis, crystal structure analysis and pharmacological evaluation. Organic and Biomolecular Chemistry, 10 29: 5554-5569. doi:10.1039/c2ob25420d
Gorja, Dhilli Rao, Kumar, K. Shiva, Kandale, Ajit, Meda, Chandana Lakshmi T., Parsa, Kishore V. L., Mukkanti, K. and Pal, Manojit (2012) ChemInform Abstract: Design and Synthesis of 4-Alkynyl Pyrazoles as Inhibitors of PDE4: A Practical Access via Pd/C-Cu Catalysis. ChemInform, 43 34: . doi:10.1002/chin.201234113
Reddy, T. Shyamsunder, Kumar, K. Shiva, Meda, Chandana L. T., Kandale, Ajit, Rambabu, D., Krishna, G. Rama, Hariprasad, C., Rao, V. Venugopala, Venkataiah, S., Reddy, C. Malla, Naidu, A., Dubey, P. K., Parsa, Kishore V. L. and Pal, Manojit (2012) Conformationally restricted novel pyrazole derivatives: synthesis of 1,8-disubstituted 5,5-dimethyl-4,5-dihydro-1H-benzo[g]indazoles as a new class of PDE4 inhibitors. Bioorganic & Medicinal Chemistry Letters, 22 9: 3248-3255. doi:10.1016/j.bmcl.2012.03.029
Gorja, Dhilli Rao, Kumar, K. Shiva, Kandale, Ajit, Meda, Chandana Lakshmi T., Parsa, Kishore V. L., Mukkanti, K. and Pal, Manojit (2012) Design and synthesis of 4-alkynyl pyrazoles as inhibitors of PDE4: a practical access via Pd/C-Cu catalysis. Bioorganic & Medicinal Chemistry Letters, 22 7: 2480-2487. doi:10.1016/j.bmcl.2012.02.008
Reddy, G. Rajeshwar, Reddy, T. Ram, Joseph, Suju C., Reddy, K. Sateesh, Meda, Chandana Lakshmi T., Kandale, Ajit, Rambabu, D., Krishna, G. Rama, Reddy, C. Malla, Parsa, Kishore V. L., Kumar, K. Shiva and Pal, Manojit (2012) Yb(OTf)(3) mediated MCR: a new and regioselective approach towards polysubstituted pyrroles of pharmacological interest. RSC Advances, 2 24: 9142-9150. doi:10.1039/c2ra21343e
Chahal, Jagbeer, Ohlyan, Renu, Kandale, Ajit, Walia, Anu and Puri, Sidharth (2011) Introduction, phytochemistry, traditional uses and biological activity of genus Piper: a review. International Journal of Current Pharmaceutical Review and Research, 2 2: 130-144.