Mr Karl Winckel
Conjoint Associate Lecturer (Princess Alexandra Hospital)
School of Pharmacy
Researcher biography
Karl Winckel is a conjoint pharmacist working between the School of Pharmacy Unversity of Queensland and the Princess Alexandra Hospital. Karl is an Advanced Practice credentialed pharmacist (stage 3) with clinical pharmacy experience in a wide range of clinical areas including cardiology, general medicine and care of the elderly. However Karl's main interest lies in education and training. Karl has coordinated and continues to coordinate training for doctors, pharmacists and nurses at the Princess Alexandra Hospital, and teaches into undergraduate and postgraduate clinical pharmacy courses at the University of Queensland. Karl co-coordinates 25-28 undergraduate student research project placements per year at the Princess Alexandra Hospital pharmacy department. Karl has co-authored 19 journal article and 1 book chapter in the last 5 years. Karl is also heavily involved in clinical education and training seminars with the Society of Hospital Pharmacists Australia (SHPA). Karl's research interests lie primarily in the clinical use of clozapine, and anticoagulants.
Book Chapter
LaCaze, Adam and Winckel, Karl (2020). Assessing drug safety assessment: metformin associated lactic acidosis. Boston studies in the philosophy and history of science. (pp. 261-287) Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-030-29179-2_12
Journal Articles
Andric, Teodora, Winckel, Karl, Tanzer, Timothy, Hollingworth, Samantha, Isoardi, Katherine and Siskind, Dan (2021). Bazett's correction formula overestimates the corrected QT among patients with antipsychotic induced tachycardia. Schizophrenia Research, 231, 22-23. doi: 10.1016/j.schres.2021.02.022
Jeffery, Bradley and Winckel, Karl (2021). Statins in AF-related strokes: A case report and literature review. Pharmacy GRIT, 4 (4), 272-275.
Siskind, Dan, Gallagher, Erin, Winckel, Karl, Hollingworth, Samantha, Kisely, Steve, Firth, Joseph, Correll, Christoph U. and Marteene, Wade (2021). Does switching antipsychotics ameliorate weight gain in patients with severe mental illness? A systematic review and meta-analysis. Schizophrenia Bulletin, 47 (4), 948-958. doi: 10.1093/schbul/sbaa191
Winckel, Karl, Sullivan, Sara, Vongphakdi, Mitt and Snoswell, Centaine L. (2020). A retrospective review examining intravenous iron infusion dosing methods. Journal of Pharmacy Practice and Research, 51 (3) jppr.1698, 225-230. doi: 10.1002/jppr.1698
George, Christopher, Barras, Michael, Coombes, Judith and Winckel, Karl (2020). Unfractionated heparin dosing in obese patients. International Journal of Clinical Pharmacy, 42 (2), 462-473. doi: 10.1007/s11096-020-01004-5
van Oosterom, Nameer, Winckel, Karl and Barras, Michael (2020). Comment on: “Stratifying therapeutic enoxaparin dose in morbidly obese patients by BMI class: a retrospective cohort study”. Clinical Drug Investigation, 40 (3), 287-288. doi: 10.1007/s40261-020-00889-4
Winckel, Karl, Daglish, Mark, Pache, David and Hollingworth, Samantha A. (2020). Time to rethink our approach to the Pharmaceutical Benefits Scheme (PBS) listing of medicines: the case of pregabalin. Australian Health Review, 45 (2), 261-262. doi: 10.1071/ah20060
Marteene, Wade, Winckel, Karl, Hollingworth, Sam, Kisely, Steve, Gallagher, Erin, Hahn, Margaret, Ebdrup, Bjørn H, Firth, Joseph and Siskind, Dan (2019). Strategies to counter antipsychotic-associated weight gain in patients with schizophrenia. Expert Opinion on Drug Safety, 18 (12), 1-12. doi: 10.1080/14740338.2019.1674809
Pham, Betty, Winckel, Karl and Snoswell, Centaine L. (2019). Ivabradine in patients with left-ventricular dysfunction and coronary artery disease. Pharmacy Growth, Research, Innovation and Training (Pharmacy GRIT), 3 (2), 131-132.
van Oosterom, Nameer, Winckel, Karl and Barras, Michael (2019). Evaluation of weight based enoxaparin dosing on anti-Xa concentrations in patients with obesity. Journal of Thrombosis and Thrombolysis, 48 (3), 387-393. doi: 10.1007/s11239-019-01847-4
McArdle, P. A., De Mel, V., DeMonte, V., Winckel, K., Gore-Jones, V., Foley, S., Korman, N., Parker, S., Dark, F. and Siskind, D. (2019). An investigation into the relationship between clozapine treatment and cognitive performance in patients with treatment resistant schizophrenia. Schizophrenia Research, 206, 450-451. doi: 10.1016/j.schres.2018.11.030
Barras, M.A. and Winckel, K. (2019). Primary and secondary prevention of stroke. Australian Pharmacist, 12, 42-51.
Hollingworth, Samantha A., Winckel, Karl, Saiepour, Nargess, Wheeler, Amanda J., Myles, Nicholas and Siskind, Dan (2018). Clozapine-related neutropenia, myocarditis and cardiomyopathy adverse event reports in Australia 1993-2014 (vol 235, pg 1915, 2018). Psychopharmacology, 235 (7), 2193-2193. doi: 10.1007/s00213-018-4909-5
Hollingworth, Samantha A., Winckel, Karl, Saiepour, Nargess, Wheeler, Amanda J., Myles, Nicholas and Siskind, Dan (2018). Clozapine-related neutropenia, myocarditis and cardiomyopathy adverse event reports in Australia 1993-2014. Psychopharmacology, 235 (7), 1915-1921. doi: 10.1007/s00213-018-4881-0
Siskind, Dan, Friend, Nadia, Russell, Anthony, McGrath, John J., Lim, Carmen, Patterson, Sue, Flaws, Dylan, Stedman, Terry, Moudgil, Vikas, Sardinha, Savio, Suetani, Shuichi, Kisely, Steve, Winckel, Karl and Baker, Andrea (2018). CoMET: a protocol for a randomised controlled trial of co-commencement of METformin as an adjunctive treatment to attenuate weight gain and metabolic syndrome in patients with schizophrenia newly commenced on clozapine. BMJ Open, 8 (3) e021000, e021000. doi: 10.1136/bmjopen-2017-021000
Siskind, Dan J., Russell, Anthony W., Gamble, Clare, Winckel, Karl, Mayfield, Karla, Hollingworth, Sam, Hickman, Ingrid, Siskind, Victor and Kisely, Steve (2017). Treatment of clozapine-associated obesity and diabetes with exenatide in adults with schizophrenia: A randomized controlled trial (CODEX). Diabetes, obesity & metabolism, 20 (4), 1050-1055. doi: 10.1111/dom.13167
Winckel, Karl and Siskind, Dan (2017). Clozapine in primary care. Australian Prescriber, 40 (6), 231-236. doi: 10.18773/austprescr.2017.067
Gupta, D., Winckel, K., Burrows, J., Ross, J. and Upham, J. W. (2017). Utilisation of nicotine replacement therapy within hospital pharmacist initiated smoking-cessation intervention - a pragmatic randomised controlled trial. Journal of Smoking Cessation, 12 (1), 1-10. doi: 10.1017/jsc.2015.14
Land, R., Siskind, D., McArdle, P., Kisely, S., Winckel, K. and Hollingworth, S. A. (2017). The impact of clozapine on hospital use: a systematic review and meta-analysis. Acta Psychiatrica Scandinavica, 135 (4), 296-309. doi: 10.1111/acps.12700
Shafiee Hanjani, Leila, Apostolidis, Anastasia, Winckel, Karl and Burrows, Judith A. (2016). An evaluation of the utilisation of the Medication Action Plan form in a tertiary hospital: what is the impact of the pharmacist?. Journal of Pharmacy Practice and Research, 47 (4), 257-262. doi: 10.1002/jppr.1237
Winckel, Karl (2016). An argument to continue statins for secondary prevention in the elderly. Australian Pharmacist, 35 (6), 66-67.
Mayfield, Karla, Siskind, Dan, Winckel, Karl, Russell, Anthony W., Kisely, Steve, Smith, Greg and Hollingworth, Samantha (2016). Glucagon-like peptide-1 agonists combating clozapine-associated obesity and diabetes. Journal of Psychopharmacology, 30 (3), 227-236. doi: 10.1177/0269881115625496
Forrester, T., Siskind, D., Winckel, K., Wheeler, A. and Hollingworth, S. (2015). Increasing Clozapine Dispensing Trends in Queensland, Australia 2004–2013. Pharmacopsychiatry, 48 (4-5), 164-169. doi: 10.1055/s-0035-1554713
Winckel, Karl, Siskind, Dan, Hollingworth, Samantha and Wheeler, Amanda (2015). Clozapine-induced myocarditis: separating the wheat from the chaff. Australian and New Zealand Journal of Psychiatry, 49 (2), 188-188. doi: 10.1177/0004867414554269
Winckel, Karl, Siskind, Dan, Hollingworth, Sam, Robinson, Gail, Mitchell, Scott, Varghese, Daniel, Smith, Lesley and Wheeler, Amanda (2015). Clozapine in the community: improved access or risky free- for-all. Australian and New Zealand Journal of Psychiatry, 49 (10), 863-865. doi: 10.1177/0004867415592957
Mayfield, Karla, Siskind, Dan, Winckel, Karl, Hollingworth, Samantha, Kisely, Steve and Russell, Anthony W. (2015). Treatment of clozapine-associated obesity and diabetes with exenatide (CODEX) in adults with schizophrenia: study protocol for a pilot randomised controlled trial. BJPsych Open, 1 (1), 67-73. doi: 10.1192/bjpo.bp.115.001073
Gujral, Gina, Winckel, Karl, Nissen, Lisa M. and Cottrell, W. Neil (2014). Impact of community pharmacist intervention discussing patients' beliefs to improve medication adherence. International Journal of Clinical Pharmacy, 36 (5), 1048-1058. doi: 10.1007/s11096-014-9993-y
Winckel, Karl and Percival, Matt (2014). In defence of Metformin. Australian Pharmacist, 33 (2), 66-69.
Winckel, Karl (2011). Psoriasis. Australian Pharmacist, 29 (11), 966-970.
Pattanaworasate, Wararat, Emmerton, Lynne M., Pulver, Lisa and Winckel, Karl H. (2010). Comparison of prescribing criteria in hospitalised Australian elderly. Pharmacy Practice, 8 (2), 132-138. doi: 10.4321/S1886-36552010000200008
Winckel, K., Nissen, L. and Cottrell, N. (2007). Horizontal integration between quality use of medicines and multi-professional education: the University of Queensland experience. Pharmacy Education, 7 (3), 29-29.
Conference Papers
Andric, T., Winckel, K., Tanzer, T., Siskind, D., Hollingworth, S., Smith, L. and Isoardi, K. (2021). Inaccurate QT interval estimation in people taking antipsychotics: are we contributing to misinformed treatment decisions?. National Medicines Symposium, Online, 18 May 2021.
Li, Catherine , Winckel, Karl , Oliver, Adrian and Hollingworth, Sam (2021). Inpatient hypoglycaemia in a digital hospital: What does it look like in numbers . PAH Health Symposium , Princess Alexandra Hospital, Brisbane, Australia, 23-27 August 2021.
Winckel, Karl, Sullivan, Sara, Vongphakdi, Mitt and Snoswell, Centaine (2021). Intravenous iron dosing. National Medicines Symposium, Australia (Virtual), 18 May 2021.
Wood, A.J, Tyler, S., Spiller, K., Fellows, N., Winckel, K., Searles, J., Thomson, B. and Cooke, G. (2020). Evaluation of interprofessional new graduate education: a pilot study in a quaternary hospital. ANZAHPE, Melbourne, VIC Australia (online), 12-15th July 2020.
Van Oosterom, N., Barras, M. and Winckel, K. (2019). Evaluation of weight based enoxaparin dosing on anti-Xa concentrations in patients with obesity. Princess Alexandra Hospital (PAH) Health Symposium., Brisbane, QLD, Australia, 31 July 2019.
Waddell, Jason, House, Lee and Winckel, Karl (2019). Assessing pharmacists adventures in the digital age. In: SHPA MM2019, Gold Coast, QLD Australia, (). 21-22 November 2019.
Li, Catherine, Pinkerton, Eve and Winckel, Karl (2019). SGLT21-associated ketoacidosis a growing epidemic: a need for a consumer-friendly infographic. In: SHPA MM2019, Gold Coast, QLD Australia, (). 21-22 November 2019.
Pinkerton, E., Winckel, K. and Forrester, T. (2019). The ketone crisis. Drug use evaluation of SGLT2 inhibitors and ketoacidosis. SHPA MM2019, Gold Coast, QLD Australia, 14-16 November 2019.
Vongphakdi, M., Winckel, K. and Sullivan, S. (2019). Dosing intravenous iron: keep it simple. SHPA mm2019, Gold Coast, QLD, Australia, 14-16 November 2019.
Edmonds, M., Winckel, K., Cameron, C. and Powell, H. (2019). The phosphate debate: intravenous vs Oral. Princess Alexandra Hospital (PAH) Health Symposium, Princess Alexandra Hospital (PAH) Brisbane, 31 July 2019.
Woodruff, Gemma, Hendy, Anna, Coombes, Judith, Winckel, Karl, Hale, Andrew, Coombes, Ian and Barras, Michael (2019). Final foundation residency portfolio reviews – Feedback from a two-site review process. APSA 2019, Melbourne, Australia, 1-4 December 2019.
Michael, Hayley, Hill, Courtney, Winckel, Karl and Norman Ilich (2019). The appropriateness of rivaroxaban drug level monitoring and the impact on clinical management in patients. SHPA mm2019, Gold Coast, Australia, 14-16 November 2019.
Siskind, Dan, Russell, Anthony, Gamble, Clare, Winckel, Karl, Hollingworth, Sam and Kisely, Steve (2018). Treatment of clozapine-associated obesity and diabetes with exenatide (Codex) in adults with schizophrenia: a randomised controlled trial. 6th Biennial Conference of the Schizophrenia International Research Society (SIRS), Florence, Italy, 4-8 April 2018. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/schbul/sby016.436
Cheng, Vesa , Forrester, Tori , Hill, Courtney , Slater, Theresa , Winckel, Karl and Coombes, Judith (2018). It's time to re-design safe prescribing education for digital hospitals!. SHPA Medicines Management 2018, Brisbane, Australia, 22-25 November 2018.
Siskind, D., Mayfield, K., Winckel, K., Hollingworth, S. and Kisely, S. (2018). Treatment of clozapine-associated obesity and diabetes with exenatide (CODEX): a pilot randomised controlled trial. SHPA MM2019, Brisbane, Australia, 22-25 November 2019.
George, C., Winckel, K., Barras, M., Coombes, J. and Cottrell, N. (2018). Dosing of Unfractionated Heparin in obese patients at the Princess Alexandra Hospital. Translational Research Institute Symposium, Brisbane, QLD, Australia, August 2018.
Rofail, Serena, Hickey, Annabel, Winckel, Karl , Adsett, Julie and Bennett, Sasha (2015). Heart Online: A toolkit for Cardiovascular Medication Management. Australian Disease Management Association (ADMA), Brisbane, Australia, 10-11th September 2015.
Tyler, S., Winckel, K., Myers, B. and House, L. (2015). Is there any value in pre-registration pharmacists learning from nurses. Pharmacy Education Symposium 2015, Prato, Italy, 4 July 2015.
Siskind, D., Kolomensky, A., Winckel, K., Wheeler, A. and Hollingworth, S. (2015). Reported Clozapine-Related Adverse Drug Reactions in Australia 1993-2013. RANZCP 2015 Congress, Brisbane, QLD Australia, 3-7 May 2015. London, United Kingdom: Sage Publications. doi: 10.1177/0004867415578344
Forrester, V., Hollingworth, S., Winckel, K., Wheeler, A. and Siskind, D. (2014). Clozapine dispensing trends: using dispensing histories to identify use. Metro South Health Allied Health Showcase, Princess Alexandra Hospital, Brisbane, 17th October 2014.
Hollingworth, S., Forrester, V., Winckel, K., Wheeler, A. and Siskind, D. (2014). Shaping the future of clozapine: safety implications of increased use. National Medicines Symposium 2014, Brisbane, QLD Australia, 21 - 23 May 2014.
Winckel, K. (2014). Metformin-lost in translation. National Medicines Symposium 2014, Brisbane, QLD Australia, 21 - 23 May 2014.
Siskind, D., Forrester, V., Hollingworth, S., Winckel, K. and Wheeler, A. (2014). Clozapine dispensing trends 2004-2013. Royal Australian and New Zealand College of Psychiatrists Annual Congress (RANZCP 2014 Congress), Perth Australia, 11-15 May 2014.
Joyce, C. and Winckel, K. (2014). Interim medication administration records (IMAR’s) in residential aged care facilities: are they effective. SHPA Conference, Cairns, QLD, Australia, 19-22 September 2014.
Gupta, D., Upham, J., Winckel, K., Burrows, J. and Ross, J. (2014). Utilisation of nicotine replacement therapy with hospital pharmacist initiated smoking cessation intervention. Metro South Heath: Allied Health Showcase 2014, Annerley, QLD, Australia, 17 October, 2014.
Siskind, Dan, Hollingworth, Samantha, Winckel, Karl and Wheeler, Amanda (2014). Clozapine: Safety implications of increased usage. Royal Australian & New Zealand College of Psychiatrists’ Annual Congress, Brisbane Australia, 3-7 May 2015. London United Kingdom: Sage Publications. doi: 10.1177/0004867414529061
Gupta, Deepali, Upham, John, Winckel, Karl, Burrows, Judith and Ross, Judy (2014). Utilisation of nicotine replacement therapy (NRT) with a hospital pharmacist initiated smoking-cessation intervention. Medicines Management 2014: 40th SHPA Conference, Darwin, Australia, 11-14 September 2014. Barton, ACT, Australia: Kaigi Conferencing and Events.
Winckel, Karl (2013). An evaluation of adherence to personal discharge medication plans. 39th SHPA National Conference, Cairns, Australia, 19-22 September 2013.
Currey, Elizabeth, Mehta, Abhishek, Winckel, Karl and Coombes, Judith (2013). Assessing the impact of a 13-week trial of extending clinical pharmacy services to the emergency department. 39th SHPA National Conference, Cairns, Australia, 19-22 September 2013.
Winckel, K. and Wu, X. (2012). Adherence to medications after discharge. National Medicines Symposium, Sydney, Australia, 24-25 May 2012.
Gujral, Gina, Winckel, Karl H., Garrahy, P, Nissen, Lisa M. and Cottrell, Neil (2011). Does promoting opinions about medications in patients with acute coronary syndrome improve adherence: A randomised controlled trial - six month interim results. Proceedings of the Princess Alexandra Hospital Health Symposium, Brisbane, September 6-9 2011.
Gujral, Gina, Winckel, Karl H., Nissen, Lisa M. and Cottrell, Neil (2011). Does promoting patients' personal understanding about medications for acute coronary syndrome improve adherence: Use of the repertory grid technique. Proceedings of the 46th ASHP Midyear Clinical Meeting & Exhibition, New Orleans, December 4-8 2011.
Gujral, Gina, Winckel, Karl H., Garrahy, P., Nissen, Lisa M. and Cottrell, Neil (2011). Pharmacists reinforcing patients' beliefs about medications to improve adherence post myocardial infarction. APSA Annual Conference 2011, Adelaide, Australia, 11-14 December 2011.
Gujral, Gina, Winckel, Karl H., Garrahy, P., Nissen, Lisa M. and Cottrell, Neil (2011). Changes in medication beliefs over time in adherent and non-adherent patients post myocardial infarction. APSA Annual Conference 2011, Adelaide, Australia, December 11-14 2011.
Burrows, J., Winckel, K. and Whitfield, K. (2011). Outcomes of a structured clinical placement as part of the curriculum for international students in a postgraduate clinical pharmacy program. Monash Pharmacy Education Symposium 2011, Prato, Italy, 11 - 13 July 2011.
Gujral, Gina, Cottrell, Neil, Nissen, Lisa M. and Winckel, Karl H. (2010). Medication beliefs in patients with acute coronary syndrome one month after discharge from hospital - a novel interview method using the repertory grid technique. National Medicines Symposium 2010, Melbourne, 26-28 May 2010.
Gujral, Gina, Winckel, Karl, Nissen, Lisa and Cottrell, Neil (2010). Beliefs towards medications for acute coronary syndrome and their relation to adherence one month after hospital discharge. 16ISPW: 6th International Social Pharmacy Workshop: Communication and Information in Pharmacy, Lisbon, Portugal, 23- 26 August 2010. Redondela, Spain: Centro de Investigaciones y Publicaciones Farmaceuticas.
Emmerton, Lynne, Pattanaworasate, Nancy, Pulver, Lisa and Winckel, Karl (2007). Comparison of three prescribing criteria in the Australian elderly. Annual Conference of the Australasian Pharmaceutical Science Association, Sydney, NSW, Australia, 8 - 11 December, 2007. Mount Waverley, Victoria: Australasian Pharmaceutical Science Association.
Cottrell, N., Nissen, L. and Winckel, K. (2007). Horizontal Integration between Quality Use of Medicines and Multi-professional Education: the University of Queensland Experience. Second International Clinical Skills Conference: Teaching, learning and assessing clinical skills: does one size fit all?, Prato Monash Centre, Tuscany, Italy, 1 - 4 July 2007.
Winckel, K. H. (2004). A case of risperidone induced delirium. SHPA Qld Branch Conference, Toowoomba, 16-18 July 2004. Australia: SHPA.