Dr Michael Milevskiy
Honorary Senior Research Fellow
School of Pharmacy and Pharmaceutical Sciences
Book Chapter
Sandhu, Gurveen K., Milevskiy, Michael J.G., Wilson, Wesley, Shewan, Annette M. and Brown, Melissa A. (2016). Non-coding RNAs in mammary gland development and disease. Non-coding RNA and the Reproductive System. (pp. 121-153) edited by Wilhelm, D and Bernard, P. New York, United States: Springer . doi: 10.1007/978-94-017-7417-8_7
Journal Articles
Pascual, Rosa, Cheng, Jinming, De Smet, Amelia H, Capaldo, Bianca D, Tsai, Minhsuang, Kordafshari, Somayeh, Vaillant, François, Song, Xiaoyu, Giner, Göknur, Milevskiy, Michael J G, Jackling, Felicity C, Pal, Bhupinder, Dite, Toby, Yousef, Jumana, Dagley, Laura F, Smyth, Gordon K, Fu, Naiyang, Lindeman, Geoffrey J, Chen, Yunshun and Visvader, Jane E (2025). Fibroblast hierarchy dynamics during mammary gland morphogenesis and tumorigenesis. EMBO Journal 16878. doi: 10.1038/s44318-025-00422-3
Dawson, Caleb A., Milevskiy, Michael J.G., Capaldo, Bianca D., Yip, Raymond K.H., Song, Xiaoyu, Vaillant, François, Prokopuk, Lexie, Jackling, Felicity C., Smyth, Gordon K., Chen, Yunshun, Lindeman, Geoffrey J. and Visvader, Jane E. (2024). Hormone-responsive progenitors have a unique identity and exhibit high motility during mammary morphogenesis. Cell Reports, 43 (12) 115073, 115073. doi: 10.1016/j.celrep.2024.115073
Bong, Alice H. L., Robitaille, Mélanie, Lin, Sichun, McCart-Reed, Amy, Milevskiy, Michael, Angers, Stéphane, Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2024). TMCO1 is upregulated in breast cancer and regulates the response to pro-apoptotic agents in breast cancer cells. Cell Death Discovery, 10 (1) 421, 1-12. doi: 10.1038/s41420-024-02183-0
So, Choon Leng, Robitaille, Mélanie, Sadras, Francisco, McCullough, Michael H., Milevskiy, Michael J. G., Goodhill, Geoffrey J., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2024). Cellular geometry and epithelial-mesenchymal plasticity intersect with PIEZO1 in breast cancer cells. Communications Biology, 7 (1) 467, 1-14. doi: 10.1038/s42003-024-06163-z
Joyce, Rachel, Pascual, Rosa, Heitink, Luuk, Capaldo, Bianca D., Vaillant, François, Christie, Michael, Tsai, Minhsuang, Surgenor, Elliot, Anttila, Casey J. A., Rajasekhar, Pradeep, Jackling, Felicity C., Trussart, Marie, Milevskiy, Michael J. G., Song, Xiaoyu, Li, Mengbo, Teh, Charis E., Gray, Daniel H. D., Smyth, Gordon K., Chen, Yunshun, Lindeman, Geoffrey J. and Visvader, Jane E. (2024). Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers. Nature Cell Biology, 26 (1), 138-152. doi: 10.1038/s41556-023-01315-5
Milevskiy, Michael J.G., Coughlan, Hannah D., Kane, Serena R., Johanson, Timothy M., Kordafshari, Somayeh, Chan, Wing Fuk, Tsai, Minhsuang, Surgenor, Elliot, Wilcox, Stephen, Allan, Rhys S., Chen, Yunshun, Lindeman, Geoffrey J., Smyth, Gordon K. and Visvader, Jane E. (2023). Three-dimensional genome architecture coordinates key regulators of lineage specification in mammary epithelial cells. Cell Genomics, 3 (11) 100424, 1-20. doi: 10.1016/j.xgen.2023.100424
Shah, Jaynish S., Milevskiy, Michael J. G., Petrova, Veronika, Au, Amy Y. M., Wong, Justin J. L., Visvader, Jane E., Schmitz, Ulf and Rasko, John E. J. (2022). Towards resolution of the intron retention paradox in breast cancer. Breast Cancer Research, 24 (1) 100, 1-11. doi: 10.1186/s13058-022-01593-1
Heitink, Luuk, Whittle, James R., Vaillant, François, Capaldo, Bianca D., Dekkers, Johanna F., Dawson, Caleb A., Milevskiy, Michael J. G., Surgenor, Elliot, Tsai, Minhsuang, Chen, Huei-Rong, Christie, Michael, Chen, Yunshun, Smyth, Gordon K., Herold, Marco J., Strasser, Andreas, Lindeman, Geoffrey J. and Visvader, Jane E. (2022). In vivo genome-editing screen identifies tumor suppressor genes that cooperate with Trp53 loss during mammary tumorigenesis. Molecular Oncology, 16 (5), 1119-1131. doi: 10.1002/1878-0261.13179
Maklad, Ahmed, Sedeeq, Mohammed, Milevskiy, Michael J. G. and Azimi, Iman (2021). Calcium signalling in medulloblastoma: an in silico analysis of the expression of calcium regulating genes in patient samples. Genes, 12 (9) 1329, 1-18. doi: 10.3390/genes12091329
Pal, Bhupinder, Chen, Yunshun, Milevskiy, Michael J. G., Vaillant, François, Prokopuk, Lexie, Dawson, Caleb A., Capaldo, Bianca D., Song, Xiaoyu, Jackling, Felicity, Timpson, Paul, Lindeman, Geoffrey J., Smyth, Gordon K. and Visvader, Jane E. (2021). Single cell transcriptome atlas of mouse mammary epithelial cells across development. Breast Cancer Research, 23 (1) 69, 1-19. doi: 10.1186/s13058-021-01445-4
Bong, Alice H. L., Robitaille, Mélanie, Milevskiy, Michael J. G., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2019). NCS-1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin. Molecular Oncology, 14 (1) 1878-0261.12589, 87-104. doi: 10.1002/1878-0261.12589
Azimi, Iman, Milevskiy, Michael J. G., Chalmers, Silke B., Yapa, Kunsala T. D. S., Robitaille, Mélanie, Henry, Christopher, Baillie, Gregory J., Thompson, Erik W., Roberts-Thomson, Sarah J and Monteith, Gregory R (2019). ORAI1 and ORAI3 in breast cancer molecular subtypes and the identification of ORAI3 as a hypoxia sensitive gene and a regulator of hypoxia responses. Cancers, 11 (2) 208, 208. doi: 10.3390/cancers11020208
Milevskiy, Michael J. G., Gujral, Udai, Del Lama Marques, Carolina, Stone, Andrew, Northwood, Korinne, Burke, Lez J., Gee, Julia M. W., Nephew, Kenneth, Clark, Susan and Brown, Melissa A. (2019). MicroRNA-196a is regulated by ER and is a prognostic biomarker in ER+ breast cancer. British Journal of Cancer, 120 (6), 621-632. doi: 10.1038/s41416-019-0395-8
Fu, Nai Yang, Pal, Bhupinder, Chen, Yunshun, Jackling, Felicity C., Milevskiy, Michael, Vaillant, François, Capaldo, Bianca D., Guo, Fusheng, Liu, Kevin H., Rios, Anne C., Lim, Nicholas, Kueh, Andrew J., Virshup, David M., Herold, Marco J., Tucker, Haley O., Smyth, Gordon K., Lindeman, Geoffrey J. and Visvader, Jane E. (2018). Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence. Developmental Cell, 47 (5), 629-644.e8. doi: 10.1016/j.devcel.2018.10.001
Milevskiy, Michael J. G., Sandhu, Gurveen K., Wronski, Anna, Korbie, Darren, Brewster, Brooke L., Shewan, Annette, Edwards, Stacey L., French, Juliet D. and Brown, Melissa A. (2018). MiR-29b-1-5p is altered in BRCA1 mutant tumours and is a biomarker in basal-like breast cancer. Oncotarget, 9 (71), 33577-33588. doi: 10.18632/oncotarget.26094
Michalak, Ewa M., Milevskiy, Michael J. G., Joyce, Rachel M., Dekkers, Johanna F., Jamieson, Paul R., Pal, Bhupinder, Dawson, Caleb A., Hu, Yifang, Orkin, Stuart H., Alexander, Warren S., Lindeman, Geoffrey J., Smyth, Gordon K. and Visvader, Jane E. (2018). Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids. PLoS Biology, 16 (8) e2004986, e2004986-8. doi: 10.1371/journal.pbio.2004986
Peters, A. A., Jamaludin, S. Y. N., Yapa, K. T. D. S., Chalmers, S., Wiegmans, A. P., Lim, H. F., Milevskiy, M. J. G., Azimi, I., Davis, F. M., Northwood, K. S., Pera, E., Marcial, D. L., Dray, E., Waterhouse, N. J., Cabot, P. J., Gonda, T. J., Kenny, P. A., Brown, M. A., Khanna, K. K., Roberts-Thomson, S. J. and Monteith, G. R. (2017). Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cells. Oncogene, 36 (46), 6490-6500. doi: 10.1038/onc.2017.234
Azimi, Iman, Milevskiy, Michael J. G., Kaemmerer, Elke, Turner, Dane, Yapa, Kunsala T. D. S., Brown, Melissa A., Thompson, Erik W., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2017). TRPC1 is a differential regulator of hypoxia-mediated events and Akt signalling in PTEN-deficient breast cancer cells. Journal of Cell Science, 130 (14), 2292-2305. doi: 10.1242/jcs.196659
Milevskiy, Michael J. G., Al-Ejeh, Fares, Saunus, Jodi M., Northwood, Korinne S., Bailey, Peter J., Betts, Joshua A., McCart Reed, Amy E., Nephew, Kenneth P., Stone, Andrew, Gee, Julia M. W., Dowhan, Dennis H., Dray, Eloise, Shewan, Annette M., French, Juliet D., Edwards, Stacey L., Clark, Susan J., Lakhani, Sunil R. and Brown, Melissa A. (2016). Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer. Human Molecular Genetics, 25 (15), 3269-3283. doi: 10.1093/hmg/ddw177
Peters, Amelia A., Milevskiy, Michael J. G., Lee, WeiC., Curry, Merril C., Smart, Chanel E., Saunus, Jodi M., Reid, Lynne, da Silva, Leonard, Marcial, Daneth L., Dray, Eloise, Brown, Melissa A., Lakhani, Sunil R., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2016). The calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin. Scientific Reports, 6 (1) 25505, 25505. doi: 10.1038/srep25505
Wronski, A., Sandhu, G. K., Milevskiy, M. J., Brewster, B. L., Bridge, J. A., Shewan, A. M., Edwards, S. L., French, J. D. and Brown, M. A. (2016). MicroRNA-206 is differentially expressed in Brca1-deficient mice and regulates epithelial and stromal cell compartments of the mouse mammary gland. Oncogenesis, 5 (4) e218, e218.1-e218.9. doi: 10.1038/oncsis.2016.27
Pera, Elena, Kaemmerer, Elke, Milevskiy, Michael J. G., Yapa, Kunsala T. D. S., O'Donnell, Jake S., Brown, Melissa A., Simpson, Fiona, Peters, Amelia A., Roberts-Thomson, Sarah J. and Monteith, Gregory R. (2016). The voltage gated Ca2+-channel Cav3.2 and therapeutic responses in breast cancer. Cancer Cell International, 16 (24) 24, 24. doi: 10.1186/s12935-016-0299-0
Gannon, Orla M., Antonsson, Annika, Milevskiy, Michael, Brown, Melissa A., Saunders, Nicholas A. and Bennett, Ian C. (2015). No association between HPV positive breast cancer and expression of human papilloma viral transcripts. Scientific Reports, 5 (18081) 18081, 18081. doi: 10.1038/srep18081
Conference Papers
Bong, A.H., Roberts-Thomson, S.J., Milevskiy, M.J. and Monteith, G.R. (2019). Abstract P2-05-08: an assessment of the potential role of intracellular Ca2+store regulators in breast cancer cells. 2018 San Antonio Breast Cancer Symposium, San Antonio, TX, United States, 4-8 December 2018. Philadelphia, PA, United States: American Association for Cancer Research (AACR). doi: 10.1158/1538-7445.sabcs18-p2-05-08
Bong, Alice H. L., Bassett, John J., Roberts-Thomson, Sarah J., Milevskiy, Michael J. G. and Monteith, Gregory R. (2017). Neuronal calcium sensor-1 (NCS-1) in the regulation of calcium homeostasis and cell death in MDA-MB-231 basal breast cancer cells. APSA-ASCEPT Joint Scientific Meeting, Brisbane, Australia, 5-8 December 2017.
Northwood, K., Saunus, J., Milevskiy, M., Lakhani, S. and Brown, M. (2017). RNA immunoprecipitation reveals lncRNA-protein interactions in basal-like breast cancer. San Antonio Breast Cancer Symposium, San Antonio TX, United States, 6-10 December 2016. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.SABCS16-P1-04-05
Northwood, orinne, Milevskiy, Michael and Brown, Melissa (2014). Investigating the role of ncRNAs in breast cancer associated DNA methylation. International Association for Breast Cancer Research, Sydney , Australia, 14-17 September 2014.
Thesis
Milevskiy, Michael J.G. (2016). Transcriptional Regulation and Function of HOXC ncRNAs in Breast Cancer. PhD Thesis, The School of Chemistry and Molecular Biosciences, The University of Queensland. doi: 10.14264/uql.2016.936