Associate Professor Amirali Popat
NHMRC Senior Research Fellow & Associate Professor
School of Pharmacy
Director of Research
+61 7 334 61870
Researcher biography
Research Interests
- Advanced Drug Delivery and Nanomedicine 1.Advanced drug delivery methods (controlled release dosage forms such as tablets, granules and microspheres) 2. Biomaterials as next generation adjuvant for vaccine delivery 3. Surface modified nanomaterials (Silica, Polymer, Liposomes) 4. Programmable nanoparticales for oral drug delivery and targeting 5. Translocation of nanoparticles after oral drug delivery (In-vitro and In-vivo)
Qualifications
- Master of Pharmaceutical Science, Gujarat University
- Bachelor of Pharmacy, Gujarat University
Featured projects | Duration |
---|---|
Functionalised Silica nano-particles for enhanced drug delivery | 2017 |
Nanoparticles for oral drug delivery |
Book Chapters
Krueger, Liam, Miles, Jared A. and Popat, Amirali (2023). 3D Printing for Novel Dosage Form Design. 3D & 4D Printing Methods for Pharmaceutical Manufacturing and Personalised Drug Delivery Opportunities and Challenges. (pp. 25-44) Cham, Switzerland: Springer. doi: 10.1007/978-3-031-34119-9_2
Rewatkar, Prarthana, Kumeria, Tushar and Popat, Amirali (2020). Size, shape and surface charge considerations of orally delivered nanomedicines. Nanotechnology for oral drug delivery. (pp. 143-176) edited by João Pedro Martins and Hélder A. Santos. London, United Kingdom: Elsevier. doi: 10.1016/b978-0-12-818038-9.00005-3
Kumeria, Tushar, Qu, Zhi, Popat, Amirali, Altalhi, Tariq and Santos, Abel (2019). Luminescent porous silicon nanoparticles for continuous wave and time-gated photoluminescence imaging. Theranostics: methods and protocols. (pp. 185-198) New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-9769-5_13
Journal Articles
Joyce, Paul, Allen, Christine J., Alonso, María José, Ashford, Marianne, Bradbury, Michelle S., Germain, Matthieu, Kavallaris, Maria, Langer, Robert, Lammers, Twan, Peracchia, Maria Teresa, Popat, Amirali, Prestidge, Clive A., Rijcken, Cristianne J. F., Sarmento, Bruno, Schmid, Ruth B., Schroeder, Avi, Subramaniam, Santhni, Thorn, Chelsea R., Whitehead, Kathryn A., Zhao, Chun-Xia and Santos, Hélder A. (2024). A translational framework to DELIVER nanomedicines to the clinic. Nature Nanotechnology. doi: 10.1038/s41565-024-01754-7
Krueger, Liam, Awad, Atheer, Basit, Abdul W., Goyanes, Alvaro, Miles, Jared A. and Popat, Amirali (2024). Clinical translation of 3D printed pharmaceuticals. Nature Reviews Bioengineering, 2 (10), 1-3. doi: 10.1038/s44222-024-00217-x
Singh, Ravi Raj, Mondal, Indranil, Janjua, Taskeen, Popat, Amirali and Kulshreshtha, Ritu (2024). Engineered smart materials for RNA based molecular therapy to treat Glioblastoma. Bioactive Materials, 33, 396-423. doi: 10.1016/j.bioactmat.2023.11.007
Moniruzzaman, Md, Janjua, Taskeen Iqbal, Martin, Jennifer H., Begun, Jakob and Popat, Amirali (2024). Cannabidiol - help and hype in targeting mucosal diseases. Journal of Controlled Release, 365, 530-543. doi: 10.1016/j.jconrel.2023.11.010
Janjua, Taskeen Iqbal, Cao, Yuxue, Kleitz, Freddy, Linden, Mika, Yu, Chengzhong and Popat, Amirali (2023). Silica nanoparticles: a review of their safety and current strategies to overcome biological barriers. Advanced Drug Delivery Reviews, 203 115115, 115115. doi: 10.1016/j.addr.2023.115115
Schmid, Roman, Volcic, Meta, Fischer, Stephan, Qu, Zhi, Barth, Holger, Popat, Amirali, Kirchhoff, Frank and Lindén, Mika (2023). Surface functionalization affects the retention and bio-distribution of orally administered mesoporous silica nanoparticles in a colitis mouse model. Scientific Reports, 13 (1) 20175, 1-17. doi: 10.1038/s41598-023-47445-6
Feng, Yuran, Cao, Yuxue, Singh, Ravi, Janjua, Taskeen Iqbal and Popat, Amirali (2023). Silica nanoparticles for brain cancer. Expert Opinion on Drug Delivery, 20 (12), 1749-1767. doi: 10.1080/17425247.2023.2273830
Bakshi, Shrishty, Pandey, Preeti, Mohammed, Yousuf, Wang, Joanna, Sailor, Michael J., Popat, Amirali, Parekh, Harendra S. and Kumeria, Tushar (2023). Porous silicon embedded in a thermoresponsive hydrogel for intranasal delivery of lipophilic drugs to treat rhinosinusitis. Journal of Controlled Release, 363, 452-463. doi: 10.1016/j.jconrel.2023.09.045
Ali, Masood, He, Yan, Chang, Anna Sze Ni, Wu, Alice, Liu, Jingyu, Cao, Yuxue, Mohammad, Yousuf, Popat, Amirali, Walsh, Laurie, Ye, Qingsong, Xu, Chun and Kumeria, Tushar (2023). Osteoimmune-modulating and BMP-2-eluting anodised 3D printed titanium for accelerated bone regeneration. Journal of Materials Chemistry B, 12 (1), 97-111. doi: 10.1039/d3tb01029e
Tyagi, Nisha, Wijesundara, Yalini H., Gassensmith, Jeremiah J. and Popat, Amirali (2023). Clinical translation of metal–organic frameworks. Nature Reviews Materials, 8 (11), 701-703. doi: 10.1038/s41578-023-00608-3
Feng, Yuran, Cao, Yuxue, Qu, Zhi, Janjua, Taskeen Iqbal and Popat, Amirali (2023). Virus-like silica nanoparticles improve permeability of macromolecules across the blood–brain barrier in vitro. Pharmaceutics, 15 (9) 2239, 2239. doi: 10.3390/pharmaceutics15092239
Krueger, Liam, Cao, Yuxue, Zheng, Zheng, Ward, Jason, Miles, Jared A. and Popat, Amirali (2023). 3D printing tablets for high-precision dose titration of caffeine. International Journal of Pharmaceutics, 642 123132, 1-9. doi: 10.1016/j.ijpharm.2023.123132
Ghodasara, Aayushi, Raza, Aun, Wolfram, Joy, Salomon, Carlos and Popat, Amirali (2023). Clinical translation of extracellular vesicles. Advanced Healthcare Materials, 12 (28) 2301010, e2301010. doi: 10.1002/adhm.202301010
Cao, Pei, Amiralian, Nasim, Wang, Jingjing, Sun, Bing, Popat, Amirali, Xie, Fengwei, Xu, Zhi Ping, Li, Yan and Li, Li (2023). Engineering nano-cellulose bio-composites to improve protein delivery for oral vaccination. Biomaterials Advances, 149 213400, 1-11. doi: 10.1016/j.bioadv.2023.213400
Meka, Anand Kumar, Gopalakrishna, Akshatha, Iriarte-Mesa, Claudia, Rewatkar, Prarthana, Qu, Zhi, Wu, Xiaoxin, Cao, Yuxue, Prasadam, Indira, Janjua, Taskeen Iqbal, Kleitz, Freddy, Kumeria, Tushar and Popat, Amirali (2023). Influence of pore size and surface functionalization of mesoporous silica nanoparticles on the solubility and antioxidant activity of confined coenzyme Q10. Molecular Pharmaceutics, 20 (6), 2966-2977. doi: 10.1021/acs.molpharmaceut.3c00017
Cao, Yuxue, Janjua, Taskeen Iqbal, Qu, Zhi, Draphoen, Bastian, Bai, Yunfan, Linden, Mika, Moniruzzaman, Md., Hasnain, Sumaira Z., Kumeria, Tushar and Popat, Amirali (2023). Virus-like silica nanoparticles enhance macromolecule permeation in vivo. Biomaterials Science, 11 (13), 4508-4521. doi: 10.1039/d3bm00137g
Janjua, Taskeen Iqbal, Cao, Yuxue, Ahmed-Cox, Aria, Raza, Aun, Moniruzzaman, Md, Akhter, Dewan Taslima, Fletcher, Nicholas L., Kavallaris, Maria, Thurecht, Kristofer J. and Popat, Amirali (2023). Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma. Journal of Controlled Release, 357, 161-174. doi: 10.1016/j.jconrel.2023.03.040
Alharthi, Sitah, Popat, Amirali, Ziora, Zyta Maria and Moyle, Peter Michael (2023). Sortase A Inhibitor Protein Nanoparticle Formulations Demonstrate Antibacterial Synergy When Combined with Antimicrobial Peptides. Molecules, 28 (5) 2114, 1-17. doi: 10.3390/molecules28052114
McKenna, Eamonn, Futrega, Kathryn, Klein, Travis J, Altalhi, Tariq A., Popat, Amirali, Kumeria, Tushar and Doran, Michael Robert (2022). Spray nebulization enables polycaprolactone nanofiber production in a manner suitable for generation of scaffolds or direct deposition of nanofibers onto cells. Biofabrication, 15 (2) 025003, 1-12. doi: 10.1088/1758-5090/aca5b7
Krueger, Liam, Miles, Jared A. and Popat, Amirali (2022). 3D printing hybrid materials using fused deposition modelling for solid oral dosage forms. Journal of Controlled Release, 351, 444-455. doi: 10.1016/j.jconrel.2022.09.032
Raza, Aun, Rossi, Gustavo Rodrigues, Janjua, Taskeen Iqbal, Souza-Fonseca-Guimaraes, Fernando and Popat, Amirali (2022). Nanobiomaterials to modulate natural killer cell responses for effective cancer immunotherapy. Trends in Biotechnology, 41 (1), 77-92. doi: 10.1016/j.tibtech.2022.06.011
Singh, Amandeep, Qu, Zhi, Sharma, Astha, Singh, Mandeep, Tse, Brian, Ostrikov, Kostya, Popat, Amirali, Sonar, Prashant and Kumeria, Tushar (2022). Ultra-bright green carbon dots with excitation-independent fluorescence for bioimaging. Journal of Nanostructure in Chemistry, 13 (3), 1-11. doi: 10.1007/s40097-022-00501-5
Alharthi, Sitah, Ziora, Zyta M., Janjua, Taskeen, Popat, Amirali and Moyle, Peter M. (2022). Formulation and biological evaluation of mesoporous silica nanoparticles loaded with combinations of sortase A inhibitors and antimicrobial peptides. Pharmaceutics, 14 (5) 986, 986. doi: 10.3390/pharmaceutics14050986
Ndayishimiye, John, Kumeria, Tushar, Popat, Amirali, Falconer, James Robert and Blaskovich, Mark A. T. (2022). Nanomaterials: the new antimicrobial magic bullet. ACS Infectious Diseases, 8 (4), 693-712. doi: 10.1021/acsinfecdis.1c00660
Ndayishimiye, John, Kumeria, Tushar, Popat, Amirali, Blaskovich, Mark A.T. and Falconer, James Robert (2022). Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazole. International Journal of Pharmaceutics, 616 121487, 121487. doi: 10.1016/j.ijpharm.2022.121487
Raza, A., Kamato, D., Sime, F.B., Roberts, J.A., Popat, A., Falconer, J.R. and Kumeria, T. (2022). Influence of PEGylated porous silicon nanoparticles on permeation and efflux of an orally administered antibiotic. Materials Today Advances, 13 100210, 100210. doi: 10.1016/j.mtadv.2022.100210
Krueger, Liam, Miles, Jared A., Steadman, Kathryn J., Kumeria, Tushar, Freeman, Christopher R. and Popat, Amirali (2022). 3D printing: potential clinical applications for personalised solid dose medications. Medical Journal of Australia, 216 (2), 64-67. doi: 10.5694/mja2.51381
Bakshi, Shrishty, Snoswell, Aaron J., Kwok, Kei Yeung, Cheng, Lung Hei, Altalhi, Tariq A., Santos, Abel, Popat, Amirali and Kumeria, Tushar (2022). Spray‐n‐Sense: sprayable nanofibers for on‐site chemical sensing. Advanced Functional Materials, 32 (16) 2103496, 2103496. doi: 10.1002/adfm.202103496
Parekh, Khushali, Hariharan, Kartik, Qu, Zhi, Rewatkar, Prarthana, Cao, Yuxue, Moniruzzaman, Md., Pandey, Preeti, Popat, Amirali and Mehta, Tejal (2021). Tacrolimus encapsulated mesoporous silica nanoparticles embedded hydrogel for the treatment of atopic dermatitis. International Journal of Pharmaceutics, 608 121079, 121079. doi: 10.1016/j.ijpharm.2021.121079
Elshaer, Dana, Moniruzzaman, Md., Ong, Yi Theng, Qu, Zhi, Schreiber, Veronika, Begun, Jakob and Popat, Amirali (2021). Facile synthesis of dendrimer like mesoporous silica nanoparticles to enhance targeted delivery of interleukin-22. Biomaterials Science, 9 (22), 7402-7411. doi: 10.1039/d1bm01352a
Cao, Pei, Wang, Jingjing, Sun, Bing, Rewatkar, Prarthana, Popat, Amirali, Fu, Changkui, Peng, Hui, Xu, Zhi Ping and Li, Li (2021). Enhanced Mucosal Transport of Polysaccharide–Calcium Phosphate Nanocomposites for Oral Vaccination. ACS Applied Bio Materials, 4 (11) acsabm.1c00798, 7865-7878. doi: 10.1021/acsabm.1c00798
Janjua, Taskeen Iqbal, Cao, Yuxue, Yu, Chengzhong and Popat, Amirali (2021). Clinical translation of silica nanoparticles. Nature Reviews Materials, 6 (12), 1-3. doi: 10.1038/s41578-021-00385-x
Cao, Yuxue, Rewatkar, Prarthana, Wang, Ran, Hasnain, Sumaira Z., Popat, Amirali and Kumeria, Tushar (2021). Nanocarriers for oral delivery of biologics: small carriers for big payloads. Trends in Pharmacological Sciences, 42 (11), 957-972. doi: 10.1016/j.tips.2021.08.005
Ang, Chee Wei, Tan, Lendl, Qu, Zhi, West, Nicholas P., Cooper, Matthew A., Popat, Amirali and Blaskovich, Mark A.T. (2021). Mesoporous silica nanoparticles improve oral delivery of antitubercular bicyclic nitroimidazoles. ACS Biomaterials Science and Engineering, 8 (10) acsbiomaterials.1c00807, 4196-4206. doi: 10.1021/acsbiomaterials.1c00807
Hallinan, Christine Mary, Eden, Edward, Graham, Myfanwy, Greenwood, Lisa-Marie, Mills, Jessica, Popat, Amirali, Truong, Linda and Bonomo, Yvonne (2021). Over the counter low-dose cannabidiol: a viewpoint from the ACRE Capacity Building Group. Journal of Psychopharmacology, 36 (6) ARTN 02698811211035394, 2698811211035394-665. doi: 10.1177/02698811211035394
Sharma, Shayna, Masud, Mostafa Kamal, Kaneti, Yusuf Valentino, Rewatkar, Prarthana, Koradia, Aayushi, Hossain, Md. Shahriar A., Yamauchi, Yusuke, Popat, Amirali and Salomon, Carlos (2021). Extracellular vesicle nanoarchitectonics for novel drug delivery applications. Small, 17 (42) 2102220, 1-22. doi: 10.1002/smll.202102220
Raza, Aun, Alavi, Seyed Ebrahim, Sime, Fekade Bruck, Han, Felicity Y., Roberts, Jason A., Popat, Amirali, Falconer, James R. and Kumeria, Tushar (2021). Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery. Acta Biomaterialia, 126, 277-290. doi: 10.1016/j.actbio.2021.03.042
Pujara, Naisarg, Giri, Rabina, Yau Wong, Kuan, Qu, Zhi, Rewatkar, Prarthana, Moniruzzaman, Md., Begun, Jakob, Ross, Benjamin P., McGuckin, Michael and Popat, Amirali (2021). pH – responsive colloidal carriers assembled from β-lactoglobulin and epsilon poly-l-lysine for oral drug delivery. Journal of Colloid and Interface Science, 589, 45-55. doi: 10.1016/j.jcis.2020.12.054
Xu, Weizhi, Zhao, Zonglan, Falconer, James, Whittaker, Andrew K., Popat, Amirali, Smith, Maree T., Kumeria, Tushar and Han, Felicity Y. (2021). Sustained release ketamine-loaded porous silicon-PLGA microparticles prepared by an optimized supercritical CO2 process. Drug Delivery and Translational Research, 12 (3), 676-694. doi: 10.1007/s13346-021-00991-w
Janjua, Taskeen Iqbal, Rewatkar, Prarthana, Ahmed-Cox, Aria, Saeed, Iqira, Mansfeld, Friederike M., Kulshreshtha, Ritu, Kumeria, Tushar, Ziegler, David S., Kavallaris, Maria, Mazzieri, Roberta and Popat, Amirali (2021). Frontiers in the treatment of glioblastoma: past, present and emerging. Advanced Drug Delivery Reviews, 171, 108-138. doi: 10.1016/j.addr.2021.01.012
Raza, Aun, Miles, Jared A., Bruck Sime, Fekade, Ross, Benjamin P., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2021). PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery. International Journal of Pharmaceutics, 597 120280, 120280. doi: 10.1016/j.ijpharm.2021.120280
Ndayishimiye, John, Popat, Amirali, Kumeria, Tushar, Blaskovich, Mark A.T. and Falconer, James Robert (2021). Supercritical carbon dioxide assisted complexation of benznidazole: γ-cyclodextrin for improved dissolution. International Journal of Pharmaceutics, 596 120240, 120240. doi: 10.1016/j.ijpharm.2021.120240
Banun, Vanessa Jane, Rewatkar, Prarthana, Chaudhary, Zanib, Qu, Zhi, Janjua, Taskeen, Patil, Anuja, Wu, Yuao, Ta, Hang T., Bansal, Nidhi, Miles, Jared A., Ross, Benjamin P., Kumeria, Tushar and Popat, Amirali (2021). Protein nanoparticles for enhanced oral delivery of coenzyme-Q10: in vitro and in silico studies. ACS Biomaterials Science and Engineering, 9 (6) acsbiomaterials.0c01354, 2846-2856. doi: 10.1021/acsbiomaterials.0c01354
Parekh, Khushali, Mehta, Tejal A., Dhas, Namdev, Kumar, Pavan and Popat, Amirali (2021). Emerging nanomedicines for the treatment of atopic dermatitis. AAPS PharmSciTech, 22 (2) 55, 55. doi: 10.1208/s12249-021-01920-3
Raza, Aun, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Falconer, James R., Kumeria, Tushar and Popat, Amirali (2021). Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem. ACS Biomaterials Science and Engineering, 7 (5) acsbiomaterials.0c01284, 1836-1853. doi: 10.1021/acsbiomaterials.0c01284
Bakshi, Shrishty, Mehta, Samriddhi, Kumeria, Tushar, Shiddiky, Muhammad J.A., Popat, Amirali, Choudhury, Sangeeta, Bose, Sudeep and Nayak, Ranu (2021). Rapid fabrication of homogeneously distributed hyper-branched gold nanostructured electrode based electrochemical immunosensor for detection of protein biomarkers. Sensors and Actuators, B: Chemical, 326 128803, 128803. doi: 10.1016/j.snb.2020.128803
Ndayishimiye, John, Cao, Yuxue, Kumeria, Tushar, Blaskovich, Mark A. T., Falconer, James Robert and Popat, Amirali (2021). Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin. Journal of Materials Chemistry B, 9 (35), 7145-7166. doi: 10.1039/d1tb01430g
Janjua, Taskeen Iqbal, Ahmed-Cox, Aria, Meka, Anand Kumar, Mansfeld, Friederike M., Forgham, Helen, Ignacio, Rosa Mistica C., Cao, Yuxue, McCarroll, Joshua A., Mazzieri, Roberta, Kavallaris, Maria and Popat, Amirali (2021). Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma. Nanoscale, 13 (40), 16909-16922. doi: 10.1039/d1nr03553c
Raza, Aun, Ngieng, Shih Chen, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2020). Oral meropenem for superbugs: challenges and opportunities. Drug Discovery Today, 26 (2), 551-560. doi: 10.1016/j.drudis.2020.11.004
Qu, Zhi, Wong, Kuan Yau, Moniruzzaman, Md., Begun, Jakob, Santos, Hélder A, Hasnain, Sumaira Z., Kumeria, Tushar, McGuckin, Michael A. and Popat, Amirali (2020). One‐pot synthesis of pH‐responsive eudragit‐mesoporous silica nanocomposites enable colonic delivery of glucocorticoids for the treatment of inflammatory bowel disease. Advanced Therapeutics, 4 (2) 2000165, 2000165. doi: 10.1002/adtp.202000165
Abeer, Muhammad Mustafa, Rewatkar, Prarthana, Qu, Zhi, Talekar, Meghna, Kleitz, Freddy, Schmid, Roman, Lindén, Mika, Kumeria, Tushar and Popat, Amirali (2020). Silica nanoparticles: a promising platform for enhanced oral delivery of macromolecules. Journal of Controlled Release, 326, 544-555. doi: 10.1016/j.jconrel.2020.07.021
Ndayishimiye, John, Popat, Amirali, Blaskovich, Mark and Falconer, James Robert (2020). Formulation technologies and advances for oral delivery of novel nitroimidazoles and antimicrobial peptides. Journal of Controlled Release, 324, 728-749. doi: 10.1016/j.jconrel.2020.05.002
Juère, Estelle, Del Favero, Giorgia, Masse, Florence, Marko, Doris, Popat, Amirali, Florek, Justyna, Caillard, Romain and Kleitz, Freddy (2020). Gastro-protective protein-silica nanoparticles formulation for oral drug delivery: In vitro release, cytotoxicity and mitochondrial activity. European Journal of Pharmaceutics and Biopharmaceutics, 151, 171-180. doi: 10.1016/j.ejpb.2020.03.015
Pujara, Naisarg, Wong, Kuan Yau, Qu, Zhi, Wang, Ran, Moniruzzaman, Md., Rewatkar, Prarthana, Kumeria, Tushar, Ross, Benjamin P., McGuckin, Michael and Popat, Amirali (2020). Oral delivery of β-lactoglobulin nanospheres encapsulated resveratrol alleviates inflammation in Winnie mice with spontaneous ulcerative colitis. Molecular Pharmaceutics, 18 (2) acs.molpharmaceut.0c00048, 627-640. doi: 10.1021/acs.molpharmaceut.0c00048
Martins, João Pedro, das Neves, José, de la Fuente, María, Celia, Christian, Florindo, Helena, Günday-Türeli, Nazende, Popat, Amirali, Santos, José Luis, Sousa, Flávia, Schmid, Ruth, Wolfram, Joy, Sarmento, Bruno and Santos, Hélder A. (2020). The solid progress of nanomedicine. Drug Delivery and Translational Research, 10 (3), 726-729. doi: 10.1007/s13346-020-00743-2
Xu, Chun, Cao, Yuxue, Lei, Chang, Li, Zhihao, Kumeria, Tushar, Meka, Anand Kumar, Xu, Jia, Liu, Jingyu, Yan, Cheng, Luo, Lihua, Khademhosseini, Ali, Popat, Amirali, He, Yan and Ye, Qingsong (2020). Polymer-mesoporous silica nanoparticle core-shell nanofibers as a dual-drug-delivery system for guided tissue regeneration. ACS Applied Nano Materials, 3 (2), 1457-1467. doi: 10.1021/acsanm.9b02298
Chaudhary, Zanib, Khan, Gul Majid, Abeer, Muhammad Mustafa, Pujara, Naisarg, Wan-Chi Tse, Brian, McGuckin, Michael A., Popat, Amirali and Kumeria, Tushar (2019). Efficient photoacoustic imaging using indocyanine green (ICG) loaded functionalized mesoporous silica nanoparticles. Biomaterials Science, 7 (12), 5002-5015. doi: 10.1039/c9bm00822e
Chaudhary, Zanib, Subramaniam, Sugarniya, Khan, Gul Majid, Abeer, Muhammad Mustafa, Qu, Zhi, Janjua, Taskeen, Kumeria, Tushar, Batra, Jyotsna and Popat, Amirali (2019). Encapsulation and controlled release of Resveratrol within functionalized mesoporous silica nanoparticles for prostate cancer therapy. Frontiers in Bioengineering and Biotechnology, 7 225, 225. doi: 10.3389/fbioe.2019.00225
Abeer, Muhammad Mustafa, Meka, Anand Kumar, Pujara, Naisarg, Kumeria, Tushar, Strounina, Ekaterina, Nunes, Rute, Costa, Ana, Sarmento, Bruno, Hasnain, Sumaira Z., Ross, Benjamin P. and Popat, Amirali (2019). Rationally designed dendritic silica nanoparticles for oral delivery of exenatide. Pharmaceutics, 11 (8) 418, 418. doi: 10.3390/pharmaceutics11080418
Sheng, Yong Hua, Wong, Kuan Yau, Seim, Inge, Wang, Ran, He, Yaowu, Wu, Andy, Patrick, Maya, Lourie, Rohan, Schreiber, Veronika, Giri, Rabina, Ng, Choa Ping, Popat, Amirali, Hooper, John, Kijanka, Gregor, Florin, Timothy H., Begun, Jakob, Radford, Kristen J., Hasnain, Sumaira and McGuckin, Michael A. (2019). MUC13 promotes the development of colitis-associated colorectal tumors via β-catenin activity. Oncogene, 38 (48), 7294-7310. doi: 10.1038/s41388-019-0951-y
Jain, Sanyog, Dongave, Shesherao M., Date, Tushar, Kushwah, Varun, Mahajan, Rahul R., Pujara, Naisarg, Kumeria, Tushar and Popat, Amirali (2019). Succinylated β-lactoglobuline-functionalized multiwalled carbon nanotubes with improved colloidal stability and biocompatibility. ACS Biomaterials Science and Engineering, 5 (7) acsbiomaterials.9b00268, 3361-3372. doi: 10.1021/acsbiomaterials.9b00268
Zhang, Yicong, Koradia, Aayushi, Kamato, Danielle, Popat, Amirali, Little, Peter J. and Ta, Hang T. (2019). Treatment of atherosclerotic plaque: perspectives on theranostics. Journal of Pharmacy and Pharmacology, 71 (7) jphp.13092, 1029-1043. doi: 10.1111/jphp.13092
Kaur, Simarpreet, Law, Cheryl Suwen, Williamson, Nathan Hu, Kempson, Ivan, Popat, Amirali, Kumeria, Tushar and Santos, Abel (2019). Environmental copper sensor based on polyethylenimine-functionalized nanoporous anodic alumina interferometers. Analytical Chemistry, 91 (8) acs.analchem.8b04963, 5011-5020. doi: 10.1021/acs.analchem.8b04963
Meka, Anand, Jenkins, Laura, Dàvalos-Salas, Mercedes, Pujara, Naisarg, Wong, Kuan, Kumeria, Tushar, Mariadason, John and Popat, Amirali (2018). Enhanced solubility, permeability and anticancer activity of vorinostat using tailored mesoporous silica nanoparticles. Pharmaceutics, 10 (4) 283, 283. doi: 10.3390/pharmaceutics10040283
Mandal, Haimanti, Katiyar, Sameer S, Swami, Rajan, Kushwah, Varun, Katare, Parmeshwar B, Kumar Meka, Anand, Banerjee, Sanjay K, Popat, Amirali and Jain, Sanyog (2018). ε-Poly-l-Lysine/plasmid DNA nanoplexes for efficient gene delivery in vivo. International Journal of Pharmaceutics, 542 (1-2), 142-152. doi: 10.1016/j.ijpharm.2018.03.021
Florin, Timothy H. J., Wright, John D., Jambhrunkar, Siddharth D., Henman, Michael G. and Popat, Amirali (2018). A well-tolerated and rapidly acting thiopurine for IBD?. Drug Discovery Today, 24 (1), 37-41. doi: 10.1016/j.drudis.2018.09.001
Juere, Estelle, Florek, Justyna, Bouchoucha, Meryem, Jambhnukar, Siddharth, Wong, Kuan Yau, Popat, Amirali and Kleitz, Freddy (2017). In vitro dissolution, cellular membrane permeability and anti-inflammatory response of resveratrol-encapsulated mesoporous silica nanoparticles. Molecular Pharmaceutics, 14 (12), 4431-4441. doi: 10.1021/acs.molpharmaceut.7b00529
Thakur, Sachin S., Ward, Micheal S., Popat, Amirali, Flemming, Nicole B., Parat, Marie-Odile, Barnett, Nigel L. and Parekh, Harendra S. (2017). Stably engineered nanobubbles and ultrasound - An effective platform for enhanced macromolecular delivery to representative cells of the retina. Plos One, 12 (5) e0178305, e0178305. doi: 10.1371/journal.pone.0178305
Nguyen, Chau T. H., Webb, Richard I., Lambert, Lynette K., Strounina, Ekaterina, Lee, Edward C., Parat, Marie-Odile, McGuckin, Michael A., Popat, Amirali, Cabot, Peter J. and Ross, Benjamin P. (2017). Bifunctional succinylated ε-polylysine-coated mesoporous silica nanoparticles for pH-responsive and intracellular drug delivery targeting the colon. ACS Applied Materials and Interfaces, 9 (11), 9470-9483. doi: 10.1021/acsami.7b00411
Tyagi, Nisha, De, Ranjit, Begun, Jakob and Popat, Amirali (2017). Cancer therapeutics with epigallocatechin-3-gallate encapsulated in biopolymeric nanoparticles. International Journal of Pharmaceutics, 518 (1-2), 220-227. doi: 10.1016/j.ijpharm.2016.12.030
Pujara, Naisarg, Jambhrunkar, Siddharth, Wong, Kuan Yau, McGuckin, Michael and Popat, Amirali (2017). Enhanced colloidal stability, solubility and rapid dissolution of resveratrol by nanocomplexation with soy protein isolate. Journal of Colloid and Interface Science, 488, 303-308. doi: 10.1016/j.jcis.2016.11.015
Lee, Edward C., Davis-Poynter, Nicholas, Nguyen, Chau T. H., Peters, Amelia A., Monteith, Gregory R., Strounina, Ekaterina, Popat, Amirali and Ross, Benjamin P. (2016). GAG mimetic functionalised solid and mesoporous silica nanoparticles as viral entry inhibitors of herpes simplex type 1 and type 2 viruses. Nanoscale, 8 (36), 16192-16196. doi: 10.1039/c6nr03878f
Summerlin, Natalie, Qu, Zhi, Pujara, Naisarg, Sheng, Yong, Jambhrunkar, Siddharth, McGuckin, Michael and Popat, Amirali (2016). Colloidal mesoporous silica nanoparticles enhance the biological activity of resveratrol. Colloids and Surfaces B: Biointerfaces, 144 (4), 1-7. doi: 10.1016/j.colsurfb.2016.03.076
Soo, Ernest, Thakur, Sachin, Qu, Zhi, Jambhrunkar, Siddharth, Parekh, Harebdra S. and Popat, Amirali (2016). Enhancing delivery and cytotoxicity of resveratrol through a dual nanoencapsulation approach. Journal of Colloid and Interface Science, 462, 368-374. doi: 10.1016/j.jcis.2015.10.022
Summerlin, Natalie, Soo, Ernest, Thakur, Sachin, Qu, Zhi, Jambhrunkar, Siddharth and Popat, Amirali (2015). Resveratrol nanoformulations: challenges and opportunities. International Journal of Pharmaceutics, 479 (2), 282-290. doi: 10.1016/j.ijpharm.2015.01.003
Abbaraju, Prasanna Lakshmi, Meka, Anand kumar, Jambhrunkar, Siddharth, Zhang, Jun, Xu, Chun, Popat, Amirali and Yu, Chengzhong (2014). Floating tablets from mesoporous silica nanoparticles. Journal of Materials Chemistry B, 2 (47), 8298-8302. doi: 10.1039/c4tb01337a
Mody, Karishma T., Mahony, Donna, Zhang, Jun, Cavallaro, Antonino S., Zhang, Bing, Popat, Amirali, Mahony, Timothy J., Yu, Chengzhong and Mitter, Neena (2014). Silica vesicles as nanocarriers and adjuvants for generating both antibody and T-cell mediated immune resposes to Bovine Viral Diarrhoea Virus E2 protein. Biomaterials, 35 (37), 9972-9983. doi: 10.1016/j.biomaterials.2014.08.044
Zhang, Jun, Raphael, Anthony P., Yang, Yannan, Popat, Amirali, Prow, Tarl W. and Yu, Chengzhong (2014). Nanodispersed UV blockers in skin-friendly silica vesicles with superior UV-attenuating efficiency. Journal of Materials Chemistry B, 2 (44), 7673-7678. doi: 10.1039/c4tb01332h
Jambhrunkar, Siddharth, Qu, Zhi, Popat, Amirali, Karmakar, Surajit, Xu, Chun and Yu, Chengzhong (2014). Modulating in vitro release and solubility of griseofulvin using functionalized mesoporous silica nanoparticles. Journal of Colloid and Interface Science, 434, 218-225. doi: 10.1016/j.jcis.2014.08.019
Jambhrunkar, Siddharth, Qu, Zhi, Popat, Amirali, Yang, Jie, Noonan, Owen, Acauan, Luiz, Ahmad Nor, Yusilawati, Yu, Chengzhong and Karmakar, Surajit (2014). Effect of surface functionality of silica nanoparticles on cellular uptake and cytotoxicity. Molecular Pharmaceutics, 11 (10), 3642-3655. doi: 10.1021/mp500385n
Popat, Amirali, Karmakar, Surajit, Jambhrunkar, Siddharth, Xu, Chun and Yu, Chengzhong (2014). Curcumin-cyclodextrin encapsulated chitosan nanoconjugates with enhanced solubility and cell cytotoxicity. Colloids and Surfaces B: Biointerfaces, 117, 520-527. doi: 10.1016/j.colsurfb.2014.03.005
Popat, Amirali, Jambhrunkar, Siddharth, Zhang, Jun, Yang, Jie, Zhang, Honwei, Meka, Anand and Yu, Chengzhong (2014). Programmable drug release using bioresponsive mesoporous silica nanoparticles for site-specific oral drug delivery. Chemical Communications, 50 (42), 5547-5550. doi: 10.1039/C4CC00620H
Xu, Chun, Niu, Yuting, Popat, Amirali, Jambhrunkar, Siddharth, Karmakar, Surajit and Yu, Chengzhong (2014). Rod-like mesoporous silica nanoparticles with rough surfaces for enhanced cellular delivery. Journal of Materials Chemistry B, 2 (3), 253-256. doi: 10.1039/c3tb21431a
Jambhrunkar, Siddharth, Karmakar, Surajit, Popat, Amirali, Yu, Meihua and Yu, Chengzhong (2014). Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin. RSC Advances, 4 (2), 709-712. doi: 10.1039/c3ra44257h
Modh, Nirav, Mehta, Dharmik, Parejiya, Punit, Popat, Amirali and Barot, Bhavesh (2014). An overview of recent patents on nanosuspension. Recent Patents on Drug Delivery and Formulation, 8 (2), 144-154. doi: 10.2174/1872211308666140422150819
Yang, Yannan, Karmakar, Surajit, Yu, Meihua, Popat, Amirali and Yu, Chengzhong (2014). Synthesis of silica vesicles with small sizes and reduced aggregation for photodynamic therapy. Chemistry Letters, Article in press (3), 316-318. doi: 10.1246/cl.130930
Mody, Karishma T., Popat, Amirali, Mahony, Donna, Cavallaro, Antonino S., Yu, Chengzhong and Mitter, Neena (2013). Mesoporous silica nanoparticles as antigen carriers and adjuvants for vaccine delivery. Nanoscale, 5 (12), 5167-5179. doi: 10.1039/c3nr00357d
Guillet-Nicolas, Rémy, Popat, Amirali, Bridot, Jean-Luc, Monteith, Gregory, Qiao, Shi Zhang and Kleitz, Freddy (2013). pH-Responsive Nutraceutical-Mesoporous Silica Nanoconjugates with Enhanced Colloidal Stability. Angewandte Chemie, 125 (8), 2374-2378. doi: 10.1002/ange.201208840
Guillet-Nicolas, Remy, Popat, Amirali, Bridot, Jean-Luc, Monteith, Gregory, Qiao, Shi Zhang and Kleitz, Freddy (2013). pH-responsive nutraceutical-mesoporous silica nanoconjugates with enhanced colloidal stability. Angewandte Chemie International Edition, 52 (8), 2318-2322. doi: 10.1002/anie.201208840
Popat, Amirali, Ross, Benjamin P., Liu, Jian, Jambhrunkar, Siddharth, Kleitz, Freddy and Qiao, Shi Zhang (2012). Enzyme-responsive controlled release of covalently bound prodrug from functional mesoporous silica nanospheres. Angewandte Chemie International, 51 (50), 12486-12489. doi: 10.1002/anie.201206416
Niu, Yuting, Popat, Amirali, Yu, Meihua, Karmakar, Surajit, Gu, Wenyi and Yu, Chengzhong (2012). Recent advance in silica-based engineered nanoparticles for gene therapy. Therapeutic Delivery, 3 (10), 1217-1237. doi: 10.4155/tde.12.98
Popat, Amirali, Liu, Jian, Lu, Gao Qing (Max) and Qiao, Shi Zhang (2012). A pH-responsive drug delivery system based on chitosan coated mesoporous silica nanoparticles. Journal of Materials Chemistry, 22 (22), 11173-11178. doi: 10.1039/c2jm30501a
Popat, Amirali, Liu, Jian, Hu, Qiuhong, Kennedy, Michael, Peters, Brenton, Lu, Gao Qing (Max) and Qiao, Shi Zhang (2012). Adsorption and release of biocides with mesoporous silica nanoparticles. Nanoscale, 4 (3), 970-975. doi: 10.1039/c2nr11691j
Popat, Amirali, Hartono, Sandy Budi, Stahr, Frances, Liu, Jian, Qiao, Shi Zhang and Lu, Gao Qing (Max) (2011). Mesoporous silica nanoparticles for bioadsorption, enzyme immobilisation, and delivery carriers. Nanoscale, 3 (7), 2801-2818. doi: 10.1039/c1nr10224a
Conference Papers
Singh, Ravi, Popat, Amirali and Kulshreshtha, Ritu (2023). Nanomedicine And Gene Therapy To Treat Glioblastoma. IBRO 11th World Congress of Neuroscience, Granada, Spain, 9-13 September 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.ibneur.2023.08.1290
Moniruzzaman, M., Rewatkar, P., Begun, J. and Popat, A. (2023). Enhancing the efficacy of cannabidiol using protein nanoparticles to treat inflammatory bowel disease. 18th Congress of ECCO, Copenhagen, Denmark, 1-4 March 2023. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjac190.0167
Thesis
Amirali Popat (2012). Porous Silica Nanoparticles for Targeted and Controlled Release of Biomolecules. PhD Thesis, Aust Institute for Bioengineering & Nanotechnology, The University of Queensland.
Patents
Florin, Timothy, Popat, Amirali and Jambhrunkar, Siddharth (2023). Extended-release formulations comprising 6-thioguanine . CA3038602C.
Florin, Timothy, Popat, Amirali and Jambhrunkar, Siddharth (2021). Novel formulation and treatment methods. US20210393638A1.
Florin, Timothy, Popat, Amirali and Jambhrunkar, Siddharth (2021). Formulation and treatment methods. US11077112B2.
Lu, Gao Qing, Qiao, Shizhang and Popat, Amirali Akbarbhai (2011). Controlled release particles and method for preparation thereof. WO2011054046A1.